The pathogenic U3271C human mitochondrial tRNA(Leu(UUR)) mutation disrupts a fragile anticodon stem.
about
A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations.Post-transcriptional nucleotide modification and alternative folding of RNASpecific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease.Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants.Structural probing of a pathogenic tRNA dimer.Mitochondrial tRNA 3' end metabolism and human disease.Unique features of animal mitochondrial translation systems. The non-universal genetic code, unusual features of the translational apparatus and their relevance to human mitochondrial diseasesTertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny.Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease.A disease-causing point mutation in human mitochondrial tRNAMet results in tRNA misfolding leading to defects in translational initiation and elongation.Pathology-related mutation A7526G (A9G) helps in the understanding of the 3D structural core of human mitochondrial tRNA(Asp).
P2860
Q24810699-C043ED92-4D47-4922-B696-59C376592CC7Q25255871-2FC2182D-3BF9-46F6-AE13-635B68619C54Q33821565-03AA43E7-5FD6-40F3-8200-3DEA8844A828Q34365724-37665A9F-7F17-4570-820A-A45BA7EB4701Q34366246-ABCF25DA-EC83-4E74-9CEA-497FAE3DB091Q35914830-AAD1C495-484C-4538-AA49-9C01C369F0AEQ36159449-141A6DB1-9775-47C4-A7EE-13D449462FD4Q37421138-F8C7B6BF-FD0C-474B-A1D1-588F141CD0BAQ37589772-79394FC1-003B-4743-AFCA-2B272D81D28CQ41502419-C6280BB6-C0AE-4943-9D20-24DB61FBC886Q42566131-98CD9FEF-9C51-4F6B-8F85-12750829284A
P2860
The pathogenic U3271C human mitochondrial tRNA(Leu(UUR)) mutation disrupts a fragile anticodon stem.
description
2003 nî lūn-bûn
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2003年の論文
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name
The pathogenic U3271C human mitochondrial tRNA
@nl
The pathogenic U3271C human mi ...... upts a fragile anticodon stem.
@en
type
label
The pathogenic U3271C human mitochondrial tRNA
@nl
The pathogenic U3271C human mi ...... upts a fragile anticodon stem.
@en
prefLabel
The pathogenic U3271C human mitochondrial tRNA
@nl
The pathogenic U3271C human mi ...... upts a fragile anticodon stem.
@en
P2860
P356
P1476
The pathogenic U3271C human mi ...... upts a fragile anticodon stem.
@en
P2093
Lisa M Wittenhagen
Marc D Roy
P2860
P304
P356
10.1093/NAR/GKG131
P407
P577
2003-01-01T00:00:00Z