Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics.
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Applications of metabolomics in cancer researchReview: toxicometabolomicsEvaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assayA method for human teratogen detection by geometrically confined cell differentiation and migrationStatistical analysis and modeling of mass spectrometry-based metabolomics data.MALDI-mass spectrometric imaging for the investigation of metabolites in Medicago truncatula root nodulesAlternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Optimization and comparison of multiple MALDI matrix application methods for small molecule mass spectrometric imaging.The human toxome projectPresent state and future perspectives of using pluripotent stem cells in toxicology researchTranslational toxicology: a developmental focus for integrated research strategies.An in vitro mechanism study on the proliferation and pluripotency of human embryonic stems cells in response to magnesium degradation.Successful drug development despite adverse preclinical findings part 2: examples.Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline.Metabolic biomarkers of prenatal alcohol exposure in human embryonic stem cell-derived neural lineages.Energy metabolism in nuclear reprogrammingOpportunities for use of human iPS cells in predictive toxicologyStem cell systems informatics for advanced clinical biodiagnostics: tracing molecular signatures from bench to bedside.Cellular reprogramming: a new technology frontier in pharmaceutical research.Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation.Standardization of pluripotent stem cell cultures for toxicity testing.Mammalian cell metabolomics: experimental design and sample preparation.The 3R principle: advancing clinical application of human pluripotent stem cells.The impact of DNA methylation technologies on drug toxicology.Contribution of new technologies to characterization and prediction of adverse effects.Advances in Applications of Metabolomics in Pluripotent Stem Cell Research.Embryonic stem cells and the next generation of developmental toxicity testing.In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities.Pluripotent stem cells: An in vitro model for nanotoxicity assessments.Metabolomic profiles delineate the potential role of glycine in gold nanorod-induced disruption of mitochondria and blood-testis barrier factors in TM-4 cells.Establishment and assessment of a new human embryonic stem cell-based biomarker assay for developmental toxicity screening.BDE-209 inhibits pluripotent genes expression and induces apoptosis in human embryonic stem cells.Non-human primate and rodent embryonic stem cells are differentially sensitive to embryotoxic compounds.Prospects and Frontiers of Stem Cell ToxicologyThe validated embryonic stem cell test to predict embryotoxicity in vitro.The effects of poly(3,4-ethylenedioxythiophene) coating on magnesium degradation and cytocompatibility with human embryonic stem cells for potential neural applications.In vitro degradation of four magnesium-zinc-strontium alloys and their cytocompatibility with human embryonic stem cells.Modern methodologies and tools for human hazard assessment of chemicalsAcute psychoactive and toxic effects of D. metel on mice explained by 1H NMR based metabolomics approach.The Opportunities of Metabolomics in Drug Safety Evaluation.
P2860
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P2860
Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Predicting human developmental ...... c stem cells and metabolomics.
@en
Predicting human developmental ...... c stem cells and metabolomics.
@nl
type
label
Predicting human developmental ...... c stem cells and metabolomics.
@en
Predicting human developmental ...... c stem cells and metabolomics.
@nl
prefLabel
Predicting human developmental ...... c stem cells and metabolomics.
@en
Predicting human developmental ...... c stem cells and metabolomics.
@nl
P2093
P1476
Predicting human developmental ...... c stem cells and metabolomics.
@en
P2093
Alan M Smith
April M Weir
Elizabeth L R Donley
Gabriela G Cezar
Paul R West
P356
10.1016/J.TAAP.2010.05.007
P577
2010-05-21T00:00:00Z