A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

Item
http://www.wikidata.org/entity/Q39707182
An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies.Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.Antiviral activity of a single-domain antibody immunotoxin binding to glycoprotein D of herpes simplex virus 2.Combination treatments with the PKC inhibitor, enzastaurin, enhance the cytotoxicity of the anti-mesothelin immunotoxin, SS1P.Pentostatin plus cyclophosphamide safely and effectively prevents immunotoxin immunogenicity in murine hosts.A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.Targeting malignant B cells with an immunotoxin against ROR1Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicityImmunogenicity of therapeutic recombinant immunotoxins.Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A.Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases.Targeted toxins in brain tumor therapy.Novel antibody-based proteins for cancer immunotherapy.Trafficking and processing of bacterial proteins by mammalian cells: Insights from chondroitinase ABC.Improving the in vivo efficacy of an anti-Tac (CD25) immunotoxin by Pseudomonas exotoxin A domain II engineering.
P2860

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

Item
http://www.wikidata.org/entity/Q39707182
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
A recombinant immunotoxin targ ...... gh antitumor activity in mice.
@en
A recombinant immunotoxin targ ...... gh antitumor activity in mice.
@nl
type
label
A recombinant immunotoxin targ ...... gh antitumor activity in mice.
@en
A recombinant immunotoxin targ ...... gh antitumor activity in mice.
@nl
prefLabel
A recombinant immunotoxin targ ...... gh antitumor activity in mice.
@en
A recombinant immunotoxin targ ...... gh antitumor activity in mice.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
A recombinant immunotoxin targ ...... igh antitumor activity in mice
@en
P2093
P304
P31
P356
10.1097/CJI.0B013E3181CD1164
P433
P478
P50
P577
P698