Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance. - Wikidata - wikimedia - TriplyDB

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance.

Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance.

http://www.wikidata.org/entity/Q39708396

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Characteristic Variations and Similarities in Biochemical, Molecular, and Functional Properties of Glyoxalases across Prokaryotes and Eukaryotes.Increased DNA dicarbonyl glycation and oxidation markers in patients with type 2 diabetes and link to diabetic nephropathy.Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.An ameliorative protocol for the quantification of purine 5',8-cyclo-2'-deoxynucleosides in oxidized DNA.Pathological significance of mitochondrial glycation Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics DNA Advanced Glycation End Products (DNA-AGEs) Are Elevated in Urine and Tissue in an Animal Model of Type 2 Diabetes.Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via Upregulation of STAT1, p53, and Bax and Downregulation of c-Myc and Bcl-2.Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect.Activity, regulation, copy number and function in the glyoxalase system.Dicarbonyl proteome and genome damage in metabolic and vascular disease.Copy number variation of glyoxalase I.A fluorogenic assay for methylglyoxal.Carbonyl stress and schizophrenia.The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases.A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes.Modulation of GLO1 Expression Affects Malignant Properties of Cells.Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples.Dicarbonyls and Advanced Glycation End-Products in the Development of Diabetic Complications and Targets for Intervention.Guanine glycation repair by DJ-1/Park7 and its bacterial homologs.Mutagenesis and repair induced by the DNA advanced glycation end product N2-1-(carboxyethyl)-2'-deoxyguanosine in human cells.Dicarbonyl stress in clinical obesity.Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation.Glyoxalase 1 copy number variation in patients with well differentiated gastro-entero-pancreatic neuroendocrine tumours (GEP-NET).Electronic cigarette: A recent update of its toxic effects on humans.A nuclear-localized rice glyoxalase I enzyme, OsGLYI-8, functions in the detoxification of methylglyoxal in the nucleus.Measurement of glyoxalase activities.Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824).

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Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance.

http://www.wikidata.org/entity/Q39708396

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

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2010年學術文章

@zh

2010年學術文章

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name

Imidazopurinones are markers o ...... d tumour multidrug resistance.

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Imidazopurinones are markers o ...... d tumour multidrug resistance.

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type

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Imidazopurinones are markers o ...... d tumour multidrug resistance.

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Imidazopurinones are markers o ...... d tumour multidrug resistance.

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Imidazopurinones are markers o ...... d tumour multidrug resistance.

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Nucleic Acids Research

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Imidazopurinones are markers o ...... d tumour multidrug resistance.

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Brigitte M Winklhofer-Roob

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Naila Rabbani

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Sahar Waris

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Thomas Fleming

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Thomas Santarius

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P2860

Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis

Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells

Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway

Endogenous DNA damage in humans: a review of quantitative data

Why do cancers have high aerobic glycolysis?

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

Quantification of N2-carboxymethyl-2'-deoxyguanosine in calf thymus DNA and cultured human kidney epithelial cells by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope dilution method

N(2)-(1-Carboxyethyl)deoxyguanosine, a nonenzymatic glycation adduct of DNA, induces single-strand breaks and increases mutation frequencies.

The glyoxalase system in health and disease.

Vitamin A, vitamin E and carotenoid status and metabolism during ageing: functional and nutritional consequences (VITAGE PROJECT).

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5432-5442

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10.1093/NAR/GKQ306

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16

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38

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Sarah Jane Larkin

Paul J Thornalley

Michael Stratton

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2010-04-30T00:00:00Z

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43534686

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20435681

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multiple drug resistance

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2938218

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