The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells.
about
TIF1beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in the myelomonocytic cell line U937Hitting bacteria at the heart of the central dogma: sequence-specific inhibitionHIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: site selection and inhibition in cell cultureSynthetic hammerhead ribozymes as tools in gene expression.Variables and strategies in development of therapeutic post-transcriptional gene silencing agentsDevelopment of lead hammerhead ribozyme candidates against human rod opsin mRNA for retinal degeneration therapy.Design of a ribozyme targeting human telomerase reverse transcriptase and cloning of it's gene.Free energy landscapes of RNA/RNA complexes: with applications to snRNA complexes in spliceosomes.Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: novel options by phosphorothioate-stimulated delivery.Theoretical design of antisense genes with statistically increased efficacy.A spermidine-induced conformational change of long-armed hammerhead ribozymes: ionic requirements for fast cleavage kinetics.Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptakeA cellular high-throughput screening approach for therapeutic trans-cleaving ribozymes and RNAi against arbitrary mRNA disease targets.Hammerhead ribozyme kinetics.Ribozyme gene therapy for autosomal dominant retinal disease.Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.
P2860
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P2860
The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The subcellular localization a ...... rmine efficacy in human cells.
@en
The subcellular localization a ...... rmine efficacy in human cells.
@nl
type
label
The subcellular localization a ...... rmine efficacy in human cells.
@en
The subcellular localization a ...... rmine efficacy in human cells.
@nl
prefLabel
The subcellular localization a ...... rmine efficacy in human cells.
@en
The subcellular localization a ...... rmine efficacy in human cells.
@nl
P2093
P2860
P356
P1476
The subcellular localization a ...... rmine efficacy in human cells.
@en
P2093
Eckstein F
Marschall P
Sczakiel G
P2860
P304
P356
10.1093/NAR/25.4.769
P407
P577
1997-02-01T00:00:00Z