Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine.
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targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysisA balancing act: efflux/influx in mycobacterial drug resistanceResistance to antibiotics targeted to the bacterial cell wallStructure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-CycloserineStructure of D-alanine-D-alanine ligase from Yersinia pestis: nucleotide phosphate recognition by the serine loopKinetic mechanism and inhibition of Mycobacterium tuberculosis D-alanine:D-alanine ligase by the antibiotic D-cycloserineA point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strainsCharacterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosisGeneration and screening of a comprehensive Mycobacterium avium subsp. paratuberculosis transposon mutant bank.Identifying feasible metabolic routes in Mycobacterium smegmatis and possible alterations under diverse nutrient conditions.Genetic Approaches to Facilitate Antibacterial Drug Development.Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila.Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.Expression, crystallization and preliminary X-ray crystallographic analysis of Xoo0352, D-alanine-D-alanine ligase A, from Xanthomonas oryzae pv. oryzae.Mycobacterium tuberculosis: drug resistance and future perspectives.Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis.Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteriaProtein targets for structure-based anti-Mycobacterium tuberculosis drug discovery.Viable screening targets related to the bacterial cell wall.Molecular basis underlying Mycobacterium tuberculosis D-cycloserine resistance. Is there a role for ubiquinone and menaquinone metabolic pathways?The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network.Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis.Identification and characterization of a NaCl-responsive genetic locus involved in survival during desiccation in Sinorhizobium meliloti.Characterization of Escherichia coli D-cycloserine transport and resistant mutants.A comprehensive survey of single nucleotide polymorphisms (SNPs) across Mycobacterium bovis strains and M. bovis BCG vaccine strains refines the genealogy and defines a minimal set of SNPs that separate virulent M. bovis strains and M. bovis BCG strDevelopment of new antituberculous agents based on new drug targets and structure-activity relationship.High-Level Heterologous Production of D-Cycloserine by Escherichia coli.Identification of novel mutations associated with cycloserine resistance in Mycobacterium tuberculosis.Advances in the treatment of pulmonary tuberculosis.Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase.Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine.Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.Hit Generation in TB Drug Discovery: From Genome to Granuloma.Overexpression of a newly identified d-amino acid transaminase in Mycobacterium smegmatis complements glutamate racemase deletion.Construction of an overexpression library forMechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell StiffnessPeptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria
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P2860
Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@en
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@nl
type
label
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@en
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@nl
prefLabel
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@en
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@nl
P2860
P1476
Roles of Mycobacterium smegmat ...... lycan inhibitor D-cycloserine.
@en
P2093
Raúl G Barletta
Zhengyu Feng
P2860
P304
P356
10.1128/AAC.47.1.283-291.2003
P407
P577
2003-01-01T00:00:00Z