ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
about
Pathogenesis of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia and mechanisms underlying its relapsePredicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemiaCell cycle control in acute myeloid leukemia.Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts.Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia.ETV6/RUNX1 induces reactive oxygen species and drives the accumulation of DNA damage in B cells.
P2860
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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2010年學術文章
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2010年學術文章
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name
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@en
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@nl
type
label
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@en
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@nl
prefLabel
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@en
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@nl
P2093
P2860
P356
P1433
P1476
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1.
@en
P2093
E R Panzer-Grümayer
P2860
P2888
P304
P356
10.1038/ONC.2010.53
P407
P577
2010-03-01T00:00:00Z