Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae.
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Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointKNL1: bringing order to the kinetochorePseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation.In-silico modeling of the mitotic spindle assembly checkpointBub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshinRecruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster.The influence of catalysis on mad2 activation dynamics.Molecular dynamics simulation on the conformational transition of the mad2 protein from the open to the closed state.The dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregationMad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint.Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC)Mad2 and Mad3 cooperate to arrest budding yeast in mitosis.Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment.Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores.In silico spatial simulations reveal that MCC formation and excess BubR1 are required for tight inhibition of the anaphase-promoting complex.Spindle assembly checkpoint is sufficient for complete Cdc20 sequestering in mitotic control.Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions.Phosphorylation regulates the p31Comet-mitotic arrest-deficient 2 (Mad2) interaction to promote spindle assembly checkpoint (SAC) activity.Systems Biology Modeling of Five Pathways for Regulation and Potent Inhibition of the Anaphase-Promoting Complex (APC/C): Pivotal Roles for MCC and BubR1.Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A.Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.Implications of alternative routes to APC/C inhibition by the mitotic checkpoint complexAnalysis of the role of GSK3 in the mitotic checkpoint
P2860
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P2860
Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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name
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@en
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@nl
type
label
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@en
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@nl
prefLabel
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@en
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@nl
P2860
P50
P356
P1476
Accumulation of Mad2-Cdc20 com ...... 2 in Saccharomyces cerevisiae.
@en
P2093
Anna De Antoni
Simonetta Piatti
P2860
P356
10.1083/JCB.200602109
P407
P577
2006-07-01T00:00:00Z