Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
about
Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9.Dexamethasone inhibits IL-9 production by human T cells.The puzzle of immune phenotypes of childhood asthmaThe development and in vivo function of T helper 9 cellsEarly-Life Exposure to Clostridium leptum Causes Pulmonary ImmunosuppressionIL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cellsIL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells.The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.Characterisation of effector mechanisms at the host:parasite interface during the immune response to tissue-dwelling intestinal nematode parasites.Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma.Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts.Importance of cytokines in murine allergic airway disease and human asthma.Nitric oxide enhances Th9 cell differentiation and airway inflammation.A brief history of IL-9IL-9 induces VEGF secretion from human mast cells and IL-9/IL-9 receptor genes are overexpressed in atopic dermatitis.The H1 histamine receptor regulates allergic lung responses.Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis.IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling.Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis.Making More MUCS.Interleukin-13 and leukotrienes: an intersection of pathogenetic schema.The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammationT cell subsets and their signature cytokines in autoimmune and inflammatory diseases.Targeting the Jak/STAT pathway for immunosuppression.Increased Serum Interleukin-9 Levels in Rheumatoid Arthritis and Systemic Lupus Erythematosus: Pathogenic Role or Just an Epiphenomenon?Cytokine Concentrations in Plasma from Children with Severe and Non-Severe Community Acquired Pneumonia.The unique features of Th9 cells and their productsGene Expression Profile of High IFN-γ Producers Stimulated with Leishmania braziliensis Identifies Genes Associated with Cutaneous LeishmaniasisRegulation of airway mucin gene expressionProgress in understanding postnatal immune dysregulation in allergic disease.Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivityEffects of interleukin-9 blockade on chronic airway inflammation in murine asthma models.Mechanisms in allergic airway inflammation - lessons from studies in the mouse.Cellular sources and immune functions of interleukin-9.IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammationAdvances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease.
P2860
Q24800600-DFEEAAA8-9A56-4B5D-9618-477C68A62453Q24804010-2EC215C2-1527-439E-9706-DDFCFC09EE8FQ26741068-18E1AFE7-9106-4B70-844F-77395E0B52D4Q28083375-9488256C-16E4-438D-AEF5-3C3BD3BCEDDBQ28393820-EC6CFF04-CBBE-4D92-80BC-F78C4E2865E9Q28590243-2AEB0427-FB95-4453-8577-DB6BE70F05DFQ33532650-E182FEAA-15E7-4B78-8EBF-6B74C1C48491Q33731751-5A372231-D0D8-430B-BDF8-A1FDEF4DAA22Q33743673-AFA85A00-2CFC-4CCC-A3B8-A49FC5F8689EQ33831073-9A0FA7F3-88EA-4F21-B97D-BBA661FF8F6DQ33900766-9A35911F-C455-4FF2-B5D4-E119D92DF9C4Q34003580-367DB031-82D3-4FE4-B5B8-D7BC14D7529EQ34037524-2195CC21-00B0-442D-9676-E1EFCBA0A997Q34168144-04B97919-A645-4FBF-8E8C-DC2B9910532EQ34193755-325C2F93-85AD-4DC3-BED7-70E82BAF7684Q34567414-CCEDB859-E360-439B-A5CA-8205FE68B51BQ34576595-90565D01-4012-4006-A002-09F48DB7884AQ34589849-39A881B7-B9B4-4884-A81F-8DC16DAEB9D8Q34629109-6FA3F922-0836-464B-B2DF-238C666E8DE1Q34653064-B876D396-B626-4D7F-A9EC-8828430D10E9Q35069032-8EB70FF5-45C7-4D74-9522-2C6EA674E1C6Q35091277-DB44912B-2F79-4174-9B60-B952158AD23FQ35105032-16ED8E54-4A38-4C2E-AD90-12DEF4CBE2C8Q35414884-03BBB22D-E930-4A76-9CE6-00E233DDD502Q35558638-40FA66D1-52D4-4B51-883D-3B9D928D9EF4Q35579377-59AEA235-A1A7-4752-8614-949C69979D86Q35674703-C8EF4F6D-CCC3-4A9D-83AD-3F4E1E4CBD50Q35788577-34C128D6-1606-4B57-8463-5A5CB9532637Q35973941-22BB89BE-434C-4F6E-A71F-81FCC10B1CA5Q36199662-70EF9F00-E8B9-4D31-A2A5-70C5E5FCB1E3Q36216587-369E4A79-8E5C-499B-A347-76A5467B0F79Q36370942-868D8580-24C8-41B8-BCE7-6D6C659E7EC0Q36661584-7D6FCF7A-C97D-4BBD-B8E4-8DD00F308650Q36837356-A20CD271-9A75-475B-AE96-B5200F98ED07Q36962194-A36F87D4-A766-44E1-B524-912C936707B1Q37173306-6509B57A-FC41-4FEE-8019-B78ECEC55874Q37309989-FBB74193-D916-4191-9B81-6DB65089522FQ37325786-FA434493-5214-42A7-8C2F-8A774F56E792Q37397810-0E077AA0-CC18-4C2A-9CA8-46E27A95D76FQ37516982-71CFB311-8CD0-4A66-9A64-E0C49F33CA59
P2860
Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Pulmonary overexpression of IL ...... n, leading to immune pathology
@en
Pulmonary overexpression of IL ...... , leading to immune pathology.
@nl
type
label
Pulmonary overexpression of IL ...... n, leading to immune pathology
@en
Pulmonary overexpression of IL ...... , leading to immune pathology.
@nl
prefLabel
Pulmonary overexpression of IL ...... n, leading to immune pathology
@en
Pulmonary overexpression of IL ...... , leading to immune pathology.
@nl
P2093
P2860
P356
P1476
Pulmonary overexpression of IL ...... n, leading to immune pathology
@en
P2093
Prabir Ray
Richard A Flavell
Ulla-Angela Temann
P2860
P356
10.1172/JCI0213696
P407
P577
2002-01-01T00:00:00Z