Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.
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Subversion of the actin cytoskeleton during viral infectionHow HIV takes advantage of the cytoskeleton in entry and replicationHIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particlesHIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo.HIV's Nef interacts with β-catenin of the Wnt signaling pathway in HEK293 cellsHeterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 NefLIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytesHIV-1 Nef: a multifaceted modulator of T cell receptor signaling.A Conserved GPG-Motif in the HIV-1 Nef Core Is Required for Principal Nef-Activities.Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization.Epidermal growth factor receptor-PI3K signaling controls cofilin activity to facilitate herpes simplex virus 1 entry into neuronal cells.Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms.The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells.Cofilin: a redox sensitive mediator of actin dynamics during T-cell activation and migration.Actin cytoskeleton control of the comings and goings of T lymphocytes.Rho'ing in and out of cells: viral interactions with Rho GTPase signalingAdding new dimensions: towards an integrative understanding of HIV-1 spread.Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2.Pathogenic microbes manipulate cofilin activity to subvert actin cytoskeleton.HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins.Subverting Host Cell P21-Activated Kinase: A Case of Convergent Evolution across Pathogens.HIV-1 Nef and T-cell activation: a history of contradictions.Alphaherpesviral US3 kinase induces cofilin dephosphorylation to reorganize the actin cytoskeleton.Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells.Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef functionAll-Round Manipulation of the Actin Cytoskeleton by HIV.SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue
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P2860
Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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name
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@en
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@nl
type
label
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@en
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@nl
prefLabel
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@en
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@nl
P2860
P356
P1433
P1476
Lentiviral Nef proteins utiliz ...... terfere with actin remodeling.
@en
P2093
Jochen M Rudolph
Libin Abraham
P2860
P304
P356
10.1128/JVI.02467-09
P407
P577
2010-02-10T00:00:00Z