TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.
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New Developments in Chronic Myeloid Leukemia: Implications for TherapyThe non-genomic loss of function of tumor suppressors: an essential role in the pathogenesis of chronic myeloid leukemia chronic phaseRedox Modulating NRF2: A Potential Mediator of Cancer Stem Cell ResistanceMore than a Decade of Tyrosine Kinase Inhibitors in the Treatment of Solid Tumors: What We Have Learned and What the Future HoldsStem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic LeukemiaHarnessing the apoptotic programs in cancer stem-like cellsMolecular mechanisms for survival regulation of chronic myeloid leukemia stem cellsProtein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancerSignal transduction in the chronic leukemias: implications for targeted therapiesCell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegansBalancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Transforming growth factor β as regulator of cancer stemness and metastasisAffinity-based proteomics reveal cancer-specific networks coordinated by Hsp90TGF-β family signaling in stem cellsTGFβ signalling in contextMitochondria and FOXO3: breath or dieUsing functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancerKnockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C ReleaseSox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaPDE3 inhibitor and EGCG combination treatment suppress cancer stem cell properties in pancreatic ductal adenocarcinoma.Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia.FOXO1 is an essential regulator of pluripotency in human embryonic stem cells.Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinomaAging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cellsSystemic approaches identify a garlic-derived chemical, Z-ajoene, as a glioblastoma multiforme cancer stem cell-specific targeting agent.Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.Arachidonate 15-lipoxygenase is required for chronic myeloid leukemia stem cell survival.FoxO3a and disease progression.The elusive chronic myeloid leukemia stem cell: does it matter and how do we eliminate it?AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemiasA set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALLIdentification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice.FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factorsTargeting HIF1α eliminates cancer stem cells in hematological malignancies.The research on the immuno-modulatory defect of mesenchymal stem cell from Chronic Myeloid Leukemia patients.Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells.Spred2 modulates the erythroid differentiation induced by imatinib in chronic myeloid leukemia cellsA tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia.
P2860
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P2860
TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
@zh-hant
name
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@en
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@nl
type
label
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@en
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@nl
prefLabel
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@en
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@nl
P2093
P356
P1433
P1476
TGF-beta-FOXO signalling maint ...... in chronic myeloid leukaemia.
@en
P2093
Atsushi Hirao
Kazuhito Naka
Noboru Motoyama
Shinji Nakao
Takako Ooshio
Takayuki Hoshii
Teruyuki Muraguchi
Yukio Kondo
Yuko Tadokoro
P2888
P304
P356
10.1038/NATURE08734
P407
P577
2010-02-01T00:00:00Z
P5875
P6179
1047968073