Importin alpha-regulated nucleation of microtubules by TPX2.
about
Identification of a TPX2-like microtubule-associated protein in DrosophilaPhosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cellsBuilding a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora AGM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing MicrotubulesSpindle pole regulation by a discrete Eg5-interacting domain in TPX2The mechanism of spindle assembly: functions of Ran and its target TPX2"HURP on" we're off to the kinetochore!Ahead of the Curve: New Insights into Microtubule DynamicsThe base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalizationTPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux.Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module.An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis.Novel Binding of the Mitotic Regulator TPX2 (Target Protein for Xenopus Kinesin-like Protein 2) to Importin-αPutting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesisEukaryotic cells and their cell bodies: Cell Theory revisedRan is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization.Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly.Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase.Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux.Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis.Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons.Xenopus importin beta validates human importin beta as a cell cycle negative regulatorGenome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpoints.The elegans of spindle assembly.TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts.Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.Importin alpha/beta and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal.Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain.A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1.Karyopherin alpha2 is essential for rRNA transcription and protein synthesis in proliferative keratinocytesPhosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly.Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassemblyNuclear retention of importin α coordinates cell fate through changes in gene expression.Specific Cooperation Between Imp-α2 and Imp-β/Ketel in Spindle Assembly During Drosophila Early Nuclear DivisionsEmergent Properties of the Metaphase Spindle.TPX2 regulates neuronal morphology through kinesin-5 interaction.Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins.TPX2 is required for postmitotic nuclear assembly in cell-free Xenopus laevis egg extracts.Drosophila importin alpha1 performs paralog-specific functions essential for gametogenesis.Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity.
P2860
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P2860
Importin alpha-regulated nucleation of microtubules by TPX2.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
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2003年學術文章
@zh-hant
name
Importin alpha-regulated nucleation of microtubules by TPX2.
@en
Importin alpha-regulated nucleation of microtubules by TPX2.
@en-gb
Importin alpha-regulated nucleation of microtubules by TPX2.
@nl
type
label
Importin alpha-regulated nucleation of microtubules by TPX2.
@en
Importin alpha-regulated nucleation of microtubules by TPX2.
@en-gb
Importin alpha-regulated nucleation of microtubules by TPX2.
@nl
prefLabel
Importin alpha-regulated nucleation of microtubules by TPX2.
@en
Importin alpha-regulated nucleation of microtubules by TPX2.
@en-gb
Importin alpha-regulated nucleation of microtubules by TPX2.
@nl
P2093
P2860
P50
P356
P1433
P1476
Importin alpha-regulated nucleation of microtubules by TPX2.
@en
P2093
Christoph A Schatz
Eric Karsenti
Oliver J Gruss
Rachel Santarella
P2860
P304
P356
10.1093/EMBOJ/CDG195
P407
P577
2003-05-01T00:00:00Z