An improved reverse genetics system for mammalian orthoreoviruses
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Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus VariantsDiminished reovirus capsid stability alters disease pathogenesis and littermate transmissionCrystal Structure of Reovirus Attachment Protein σ1 in Complex with Sialylated OligosaccharidesThe GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 ReovirusDeterminants of strain-specific differences in efficiency of reovirus entryReverse genetics for mammalian reovirus.Experimental pathways towards developing a rotavirus reverse genetics system: synthetic full length rotavirus ssRNAs are neither infectious nor translated in permissive cells.Serotype-Specific Killing of Large Cell Carcinoma Cells by Reovirus.Efficient norovirus and reovirus replication in the mouse intestine requires microfold (M) cells.Dual selection mechanisms drive efficient single-gene reverse genetics for rotavirusAntiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphatesA post-entry step in the mammalian orthoreovirus replication cycle is a determinant of cell tropism.Glycan engagement dictates hydrocephalus induction by serotype 1 reovirus.Molecular determinants of proteolytic disassembly of the reovirus outer capsid.Reverse Genetics for Fusogenic Bat-Borne Orthoreovirus Associated with Acute Respiratory Tract Infections in Humans: Role of Outer Capsid Protein σC in Viral Replication and Pathogenesis.Mechanisms of reovirus bloodstream dissemination.An Inhibitory Motif on the 5'UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies.Comparative analysis of Reoviridae reverse genetics methods.Comparison of three neurotropic viruses reveals differences in viral dissemination to the central nervous systemThe sweet spot: defining virus-sialic acid interactions.Reovirus activates a caspase-independent cell death pathway.Engineering recombinant reoviruses with tandem repeats and a tetravirus 2A-like element for exogenous polypeptide expressionInterferon-inducible transmembrane protein 3 (IFITM3) restricts reovirus cell entry.Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1Genetic determinants of reovirus pathogenesis in a murine model of respiratory infectionAn ITAM in a nonenveloped virus regulates activation of NF-κB, induction of beta interferon, and viral spread.African Swine Fever Virus NP868R Capping Enzyme Promotes Reovirus Rescue during Reverse Genetics by Promoting Reovirus Protein Expression, Virion Assembly, and RNA Incorporation into Infectious Virions.Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus.Reovirus μ1 Protein Affects Infectivity by Altering Virus-Receptor Interactions.Lipid Membranes Facilitate Conformational Changes Required for Reovirus Cell Entry.Conformational changes required for reovirus cell entry are sensitive to pH.Replicating reoviruses with a transgene replacing the codons for the head domain of the viral spike.Amino acids 78 and 79 of Mammalian Orthoreovirus protein µNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication.The μ1 72-96 loop controls conformational transitions during reovirus cell entry.Lipids Cooperate with the Reovirus Membrane Penetration Peptide to Facilitate Particle Uncoating.A reverse genetics system of African horse sickness virus reveals existence of primary replication.Reovirus replication protein μ2 influences cell tropism by promoting particle assembly within viral inclusions.Optimum length and flexibility of reovirus attachment protein σ1 are required for efficient viral infection.Cell entry-associated conformational changes in reovirus particles are controlled by host protease activity.Characterization of a replicating mammalian orthoreovirus with tetracysteine tagged μNS for live cell visualization of viral factories.
P2860
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P2860
An improved reverse genetics system for mammalian orthoreoviruses
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
An improved reverse genetics system for mammalian orthoreoviruses
@en
An improved reverse genetics system for mammalian orthoreoviruses.
@nl
type
label
An improved reverse genetics system for mammalian orthoreoviruses
@en
An improved reverse genetics system for mammalian orthoreoviruses.
@nl
prefLabel
An improved reverse genetics system for mammalian orthoreoviruses
@en
An improved reverse genetics system for mammalian orthoreoviruses.
@nl
P2093
P2860
P1433
P1476
An improved reverse genetics system for mammalian orthoreoviruses
@en
P2093
Laura S Ooms
Mine Ikizler
Takeshi Kobayashi
Terence S Dermody
P2860
P304
P356
10.1016/J.VIROL.2009.11.037
P407
P577
2009-12-29T00:00:00Z