Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma.
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Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agentDetection of Sulfatase Enzyme Activity with a CatalyCEST MRI Contrast AgentNF-κB and stat3 transcription factor signatures differentiate HPV-positive and HPV-negative head and neck squamous cell carcinoma.2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cellsSTAT3 pathway regulates lung-derived brain metastasis initiating cell capacity through miR-21 activation.Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity.Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A EpendymomaCD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence.Assessing Combinational Drug Efficacy in Cancer Cells by Using Image-based Dynamic Response Analysis.Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.Preferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal.Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer TherapeuticsGRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy.Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic LiabilitiesHybrid antibiotics - clinical progress and novel designs.Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells.miR-30 overexpression promotes glioma stem cells by regulating Jak/STAT3 signaling pathway.STAT3 activation in infection and infection-associated cancer.Identification of Bidentate Salicylic Acid Inhibitors of PTP1B.Novel 2-Carbonylbenzo[b]thiophene 1,1-Dioxide Derivatives as Potent Inhibitors of STAT3 Signaling Pathway.Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells.Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.Pharmacologic inhibition of STAT5 in acute myeloid leukemia.Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.A new synthetic derivative of cryptotanshinone KYZ3 as STAT3 inhibitor for triple-negative breast cancer therapy
P2860
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P2860
Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
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2013年學術文章
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name
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@en
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@nl
type
label
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@en
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@nl
prefLabel
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@en
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@nl
P2093
P2860
P356
P1476
Potent Targeting of the STAT3 ...... ute for Treating Glioblastoma.
@en
P2093
Ahmed M Aman
Andriana O Jouk
Anthony J Veloso
Brent D G Page
Carly Griffin
David R Kaplan
H Artee Luchman
Kagan Kerman
Natalie Grinshtein
Patrick T Gunning
P2860
P304
P356
10.1021/ML4003138
P577
2013-09-08T00:00:00Z