Methionine recycling pathways and antimalarial drug design.
about
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosisStructure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysisStructures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide bindingMolecular Determinants of Substrate Specificity in Plant 5′-Methylthioadenosine NucleosidasesStructure ofStaphylococcus aureus5′-methylthioadenosine/S-adenosylhomocysteine nucleosidaseMechanism of substrate specificity in 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidasesEnzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidaseCrystal Structures of the Helicobacter pylori MTAN Enzyme Reveal Specific Interactions between S -Adenosylhomocysteine and the 5′-Alkylthio Binding SubsiteStructural Determinants of the 5′-Methylthioinosine Specificity of Plasmodium Purine Nucleoside PhosphorylaseStructural and biochemical characterization of Chlamydia trachomatis hypothetical protein CT263 supports that menaquinone synthesis occurs through the futalosine pathway.Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits.A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathwayMathematical modelling of polyamine metabolism in bloodstream-form Trypanosoma brucei: an application to drug target identificationEnzyme homologues have distinct reaction paths through their transition states.Assessment of methylthioadenosine/S-adenosylhomocysteine nucleosidases of Borrelia burgdorferi as targets for novel antimicrobials using a novel high-throughput methodPurification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum.Tyrosine aminotransferase catalyzes the final step of methionine recycling in Klebsiella pneumoniae.Methionine regeneration and aspartate aminotransferase in parasitic protozoaMethylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism.Tyrosine aminotransferase from Leishmania infantum: A new drug target candidateIn silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screenNovel molecular targets for antimalarial drug development.Aromatic amino acid transamination and methionine recycling in trypanosomatidsMetabolic characteristics and importance of the universal methionine salvage pathway recycling methionine from 5'-methylthioadenosine.Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.Antimalarial activities of aminooxy compounds.Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.Novel trypanocidal analogs of 5'-(methylthio)-adenosine.Crystallization and preliminary X-ray analysis of 2,3-diketo-5-methylthiopentyl-1-phosphate enolase from Bacillus subtilis.Transition-state analysis of S. pneumoniae 5'-methylthioadenosine nucleosidaseFunctional analysis of methylthioribose kinase genes in plants.A new rubisco-like protein coexists with a photosynthetic rubisco in the planktonic cyanobacteria Microcystis.
P2860
Q24805274-72D7C2B4-0BE1-4E39-A50C-4E1947A9DF81Q27640206-0244F3AA-8C87-4B77-9A5B-64B9D4AD7544Q27644865-0189875D-BCAD-45F3-BB2A-82F38198BD9BQ27650080-C26DC750-FF1D-4131-A5CA-51DE134B3129Q27650516-4310AA3E-09CB-4880-B22E-F2BEF6CB2A89Q27662360-A1247259-0464-4081-B90A-922D87475DCDQ27665126-2405FCD3-1E30-4CED-A180-8E3A0CCE377EQ27675111-820229E3-671F-435C-A7B3-44BF035D6587Q27681286-A8D34149-2230-49C1-ABC2-2E915E2A5585Q27925199-050B1B95-9A91-463C-BE96-E4514A376823Q27930662-974B01B3-D6C4-460F-B710-D35EC8442ACBQ27938927-1813CDEC-3A02-46B2-9F50-C639EAE33C05Q28476314-224839BC-BC65-4F86-8B78-2D4691E867B9Q28485261-B773F7BA-D8D4-4B7A-B985-13288B4A948BQ30635744-21E898A4-B4E5-417A-BFD0-E25F69EA4E28Q33431764-D95082D3-D2B2-4580-8CE6-D87FFB991C30Q33780149-7761DD7B-5FD9-4381-B7DB-01FB5DF440E9Q33854800-2BF1EBE4-A1F8-43C7-9613-EAD6E165222AQ33996582-C1B2E178-ADAD-4DAC-A553-FFC94CE5578DQ34672769-60C5C9C0-E9C1-4389-8344-32D27248B5C9Q34705430-26560A22-040B-4B26-93A6-4650CE6EDBB9Q36736936-BC90B79D-3DDF-4F0E-AB02-8D2C4B4602D8Q37093960-685DAC40-A28A-4E6E-984A-F657BCCF1745Q37630541-3A60B089-ED4A-4403-8EA9-6DD742C45D83Q37641189-69C40D24-7F9A-476C-9627-20969B401A20Q38474958-8E99E985-9C5D-4556-9DA4-A0B52C282F61Q39475037-2D015B9F-5493-462A-A27B-E087036F07C3Q39743843-6C0E016E-FF88-41BB-86EB-C5BFF80DE239Q41912244-DCB8FF81-BF85-4621-88D5-224C3CDA53C1Q42000978-65F76709-195D-4346-A542-B52EEDB8E7F3Q42410823-AFFA4D60-B042-48A9-B55B-22BAEF424FB9Q45158533-F8E4E812-F20B-48CD-BBC8-8E4F803E94D3Q48087070-F737DFDB-0DF2-4C0A-A636-B4F6ECC44A32
P2860
Methionine recycling pathways and antimalarial drug design.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Methionine recycling pathways and antimalarial drug design.
@en
Methionine recycling pathways and antimalarial drug design.
@nl
type
label
Methionine recycling pathways and antimalarial drug design.
@en
Methionine recycling pathways and antimalarial drug design.
@nl
prefLabel
Methionine recycling pathways and antimalarial drug design.
@en
Methionine recycling pathways and antimalarial drug design.
@nl
P2093
P2860
P356
P1476
Methionine recycling pathways and antimalarial drug design.
@en
P2093
A J Spiess
C J Bacchi
J Garofalo-Hannan
J R Sufrin
S R Meshnick
P2860
P304
P356
10.1128/AAC.39.11.2511
P407
P577
1995-11-01T00:00:00Z