A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation
about
Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingThe Ikaros family of zinc-finger proteinsRNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescenceFOXO1 transcription factor: a critical effector of the PI3K-AKT axis in B-cell development.Rationale for targeting the pre-B-cell receptor signaling pathway in acute lymphoblastic leukemia.Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemiaSelf-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate.Integrated signaling in developing lymphocytes: the role of DNA damage responses.The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization.RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.RETRACTED: The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination.Cutting edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cellsSurvival factor NFIL3 restricts FOXO-induced gene expression in cancerLymphocyte development: integration of DNA damage response signaling.B cell lymphoma in HIV transgenic mice.Prolactin levels correlate with abnormal B cell maturation in MRL and MRL/lpr mouse models of systemic lupus erythematosus-like diseaseCDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis.Balancing Proliferation with Igκ Recombination during B-lymphopoiesisToll-like receptor 4-mediated signaling regulates IL-7-driven proliferation and differentiation of B-cell precursors.Transcriptional control of early T and B cell developmental choicesThe pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia.Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia.Assembly and Function of the Precursor B-Cell Receptor.The miR-15 family reinforces the transition from proliferation to differentiation in pre-B cells.Total cellular protein presence of the transcription factor IRF8 does not necessarily correlate with its nuclear presence.Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3.Petri Net computational modelling of Langerhans cell Interferon Regulatory Factor Network predicts their role in T cell activationMK5 activates Rag transcription via Foxo1 in developing B cells.SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomasCell cycle RNA regulons coordinating early lymphocyte development.Mechanisms of central tolerance for B cells.A Chemoattractant-Guided Walk Through Lymphopoiesis: From Hematopoietic Stem Cells to Mature B Lymphocytes.The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling.PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell developmentDual Mechanism of Rag Gene Repression by c-Myb during Pre-B Cell Proliferation.The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.Metabolic gatekeeper function of B-lymphoid transcription factorsHuman pre-B cell receptor signal transduction: evidence for distinct roles of PI3kinase and MAP-kinase signalling pathways.
P2860
Q26862927-9F90E905-EB59-49D5-A75F-6F9E2265F1B3Q28066194-33246AAF-85CB-46BA-AB90-C59A59880B96Q28507888-A8034A50-D1E4-4489-8F2F-67C16D97BD84Q34405336-91342444-CEBC-4B6C-80B9-9E069B4AEFE4Q35723998-9F2DB294-D6C1-402E-A602-E266F906CE95Q35827910-C77234F8-881F-4844-AE79-4636DC6896B1Q36201677-38C6A45E-F6BE-4027-8598-BFCB2A51B7ACQ36387132-FCC1A4DB-F529-4BE8-92B2-1C4FBBB371CBQ36409603-08E6EC38-DB0B-4193-8E59-0F208283BA95Q36472229-F759A480-1A8F-4E6F-BA34-3C2FFFA7D48AQ36489294-5979A84D-CF4D-40AF-AA51-9E1164E06DFFQ36569363-14EBBE55-83AC-473B-BE59-460D6025BF15Q36759660-B42C7DAA-0A9E-442E-A4BC-791BA43D2073Q36831332-BC5242D7-EA4C-4898-8426-839F07F57D8AQ36832185-47F59D81-9673-49AE-AFDA-086B5C6D30D3Q36846366-0D6127D5-C0F6-4C0B-8571-5CB8563D56E9Q37356765-C9CA05EB-29E9-44A8-B378-B6B1E4644A5BQ37426698-5277A91A-0B27-435E-98BF-7AB47917AB9FQ37679999-8F1FC328-BDD7-4AFD-8ED3-EC80E6E4E130Q37692925-2D1B7C20-367F-4DC5-B638-5EE6F6B7EA33Q37729978-42F66C4C-4A55-4EB5-8000-6EB1ADFF1E78Q38182644-F3CC964B-F536-426F-A4E4-3B9A16089EF3Q38460308-81D245BA-0EC4-41F3-91F8-8C26888B0538Q38492313-F3A59212-F56E-4CBA-ADB3-7F149E76C1B9Q38594687-6E13FB5F-28B8-43A4-8326-34150E28B912Q38680163-014B5810-4EB7-43C8-BA70-7236B4BD5F1AQ38748747-0A0371C1-6B7C-4872-9815-8BF99A0590C8Q38801648-AF4F108A-8731-489B-B3F5-64ABEA123992Q38848941-4407EA89-E510-4C45-8E66-5E00A954E60BQ39121516-1DBCF8E7-CF9A-43F5-ACE4-2C0ED760B0D7Q39140068-B0AFD66F-D858-49BA-B492-DF50A6576146Q39148241-934649EA-A8C4-46EC-BDF7-F3468A62A7A7Q39214736-E69150CB-9727-4DB9-9827-40E5FE409698Q39245050-1D17CDD9-F1FF-4B44-8DCD-AE82E54B6341Q39455556-8E260B02-47C2-47AE-8135-5DD1DBE26A04Q39582134-D55CA5CF-9A35-42F2-904E-DDBF5F696C5CQ40260090-BCB9DE5C-D8CE-4B40-ADA6-FEBFBE46881DQ41661129-A8ABF3E9-6D7A-4CB5-BD16-C1C83B065723Q41667201-061D7AB8-85EC-46D7-B05F-33196E6DF7A0Q41867889-CF369D52-DB86-4172-8B14-E377491696F1
P2860
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A self-reinforcing regulatory ...... signaling and differentiation
@en
A self-reinforcing regulatory ...... signaling and differentiation.
@nl
type
label
A self-reinforcing regulatory ...... signaling and differentiation
@en
A self-reinforcing regulatory ...... signaling and differentiation.
@nl
prefLabel
A self-reinforcing regulatory ...... signaling and differentiation
@en
A self-reinforcing regulatory ...... signaling and differentiation.
@nl
P2093
P2860
P356
P1433
P1476
A self-reinforcing regulatory ...... signaling and differentiation
@en
P2093
Aaron R Dinner
Eric Bertolino
Harinder Singh
Joseph R Triggs
Kyoko Ochiai
Malay Mandal
Marcus R Clark
Mark Maienschein-Cline
Roger Sciammas
P2860
P304
P356
10.1038/NI.2210
P407
P577
2012-01-22T00:00:00Z