Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines.
about
Pseudomonas syringae pv. syringae uses proteasome inhibitor syringolin A to colonize from wound infection sitesThe chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity.Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones.The impact of plant-pathogen studies on medicinal drug discovery.Direct cloning, genetic engineering, and heterologous expression of the syringolin biosynthetic gene cluster in E. coli through Red/ET recombineering.Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity and Induces Tumor Cell Death.The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains.Activity-based imaging probes of the proteasome.The chemistry and biology of syringolins, glidobactins and cepafungins (syrbactins).Probes for activity-based profiling of plant proteases.Exploiting nature's rich source of proteasome inhibitors as starting points in drug development.Activity-based probes for the study of proteases: recent advances and developments.Development of Proteasome Inhibitors as Therapeutic Drugs.Peptide-based proteasome inhibitors in anticancer drug design.Enzymatic timing and tailoring of macrolactamization in syringolin biosynthesisActivity-based probes for the multicatalytic proteasome.Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma.Mining the Active Proteome of Arabidopsis thaliana.SylC catalyzes ureido-bond formation during biosynthesis of the proteasome inhibitor syringolin A.Activity-based probes for studying the activity of flavin-dependent oxidases and for the protein target profiling of monoamine oxidase inhibitorsImpact of the structures of macrocyclic Michael acceptors on covalent proteasome inhibition.Chemical strategies to unravel bacterial-eukaryotic signaling.Phosphono Bisbenzguanidines as Irreversible Dipeptidomimetic Inhibitors and Activity-Based Probes of Matriptase-2.Activity-Based Protein Profiling with Natural Product-Derived Chemical Probes in Human Cell Lysates.Total synthesis of syringolin A and improvement of its biological activity.A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.
P2860
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P2860
Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
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name
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@en
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@nl
type
label
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@en
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@nl
prefLabel
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@en
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@nl
P2093
P356
P1433
P1476
Syringolin A selectively label ...... -adapted leukaemic cell lines.
@en
P2093
André S Bachmann
Christoph Driessen
Jérôme Clerc
Marianne Kraus
Markus Kaiser
Michael Groll
Robert Dudler
Robert Huber
P304
P356
10.1002/CBIC.200900411
P577
2009-11-01T00:00:00Z