SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
about
Clinical relevance of SKP2 alterations in metastatic melanomaRASSF tumor suppressor gene family: biological functions and regulationHULC: an oncogenic long non-coding RNA in human cancerMature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells.GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis.Disruption of the histidine triad nucleotide-binding hint2 gene in mice affects glycemic control and mitochondrial function.Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice.Regulation of FOXO protein stability via ubiquitination and proteasome degradation.DCGL v2.0: an R package for unveiling differential regulation from differential co-expressionHepatitis B virus core promoter mutations contribute to hepatocarcinogenesis by deregulating SKP2 and its target, p21SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice.Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex.Numb downregulation suppresses cell growth and is associated with a poor prognosis of human hepatocellular carcinoma.Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion.New insights on the role of epigenetic alterations in hepatocellular carcinoma.Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value.HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression.Loss of miR-1258 contributes to carcinogenesis and progression of liver cancer through targeting CDC28 protein kinase regulatory subunit 1BCks1: Structure, Emerging Roles and Implications in Multiple CancersSkp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition.Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma.A portrayal of E3 ubiquitin ligases and deubiquitylases in cancer.The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations.The role and therapeutic implications of RING-finger E3 ubiquitin ligases in hepatocellular carcinoma.Long non-coding RNA expression profiles of hepatitis C virus-related dysplasia and hepatocellular carcinoma.Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition.Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis.Hint1 Up-Regulates IκBα by Targeting the β-TrCP Subunit of SCF E3 Ligase in Human Hepatocellular Carcinoma Cells.MicroRNA-153 promotes Wnt/β-catenin activation in hepatocellular carcinoma through suppression of WWOX.Hepatitis B Virus Core Promoter A1762T/G1764A (TA)/T1753A/T1768A Mutations Contribute to Hepatocarcinogenesis by Deregulating Skp2 and P53.Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.Long noncoding RNA NEAT1 promotes cell proliferation and invasion by regulating hnRNP A2 expression in hepatocellular carcinoma cells.Upregulated expression of ubiquitin-conjugating enzyme E2Q1 (UBE2Q1) is associated with enhanced cell proliferation and poor prognosis in human hapatocellular carcinoma.SiRNA-targeted carboxypeptidase D inhibits hepatocellular carcinoma growth.HBV core promoter mutations promote cellular proliferation through E2F1-mediated upregulation of S-phase kinase-associated protein 2 transcription.Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.Gene network analysis leads to functional validation of pathways linked to cancer cell growth and survival.Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.Suppression of TG-interacting factor sensitizes arsenic trioxide-induced apoptosis in human hepatocellular carcinoma cells.
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P2860
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@en
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@nl
type
label
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@en
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@nl
prefLabel
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@en
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@nl
P2093
P1433
P1476
SKP2 and CKS1 promote degradat ...... ocellular carcinoma prognosis.
@en
P2093
Diego F Calvisi
Federico Pinna
Francesco Feo
Maddalena Frau
Marcella Sini
Maria A Seddaiu
Maria L Tomasi
Maria M Simile
Maria R Muroni
Piero Bonelli
P304
1816-26.e1-10
P356
10.1053/J.GASTRO.2009.08.005
P407
P50
P577
2009-08-15T00:00:00Z