Antibody-directed enzyme prodrug therapy: a promising approach for a selective treatment of cancer based on prodrugs and monoclonal antibodies.

Antibody-directed enzyme prodrug therapy: a promising approach for a selective treatment of cancer based on prodrugs and monoclonal antibodies.

Item
http://www.wikidata.org/entity/Q39816056
Substrate mediated enzyme prodrug therapyBiodistribution of HuCC49DeltaCH2-beta-galactosidase in colorectal cancer xenograft model.Magnetic tumor targeting of β-glucosidase immobilized iron oxide nanoparticles.Synthesis, biological evaluation, and live cell imaging of novel fluorescent duocarmycin analogs.Optical imaging of targeted β-galactosidase in brain tumors to detect EGFR levelsAntibody-enzyme fusion proteins for cancer therapy.Novel 19 F-MRS β-galactosidase reporter molecules incorporated nitrogen mustard analogues.Photoactivatable prodrugs of highly potent duocarmycin analogues for a selective cancer therapy.The first generation of β-galactosidase-responsive prodrugs designed for the selective treatment of solid tumors in prodrug monotherapy.Duocarmycin analogues target aldehyde dehydrogenase 1 in lung cancer cells.A galactosidase-responsive "trojan horse" for the selective targeting of folate receptor-positive tumor cells.A novel GAP460 biopolymer for use as a carrier in drug-delivery applications.Cytosolic delivery of large proteins using nanoparticle-stabilized nanocapsules.pH-sensitive pHluorins as a molecular sensor for in situ monitoring of enzyme-catalyzed prodrug activation.The two faces of potent antitumor duocarmycin-based drugs: a structural dissection reveals disparate motifs for DNA versus aldehyde dehydrogenase 1 affinity.Biocatalytic polymer coatings: on-demand drug synthesis and localized therapeutic effect under dynamic cell culture conditions.
P2860

Antibody-directed enzyme prodrug therapy: a promising approach for a selective treatment of cancer based on prodrugs and monoclonal antibodies.

Item
http://www.wikidata.org/entity/Q39816056
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@en
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@nl
type
label
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@en
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@nl
prefLabel
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@en
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P356
P1433
P1476
Antibody-directed enzyme prodr ...... ugs and monoclonal antibodies.
@en
P2093
P2860
P304
P31
P356
10.1111/J.1747-0285.2009.00856.X
P433
P478
P577
P5875
P698
P921