Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute
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Acute lymphoblastic leukaemiaRole of Ikaros in T-cell acute lymphoblastic leukemiaThe Philadelphia chromosome in leukemogenesisGenomic profiling of B-progenitor acute lymphoblastic leukemiaCurrent concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemiaIKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.Use of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemiaThe PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party.The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution.The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia.IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemiaProtein phosphatase 1 (PP1) and Casein Kinase II (CK2) regulate Ikaros-mediated repression of TdT in thymocytes and T-cell leukemia.The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues.Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemiaA two-gene blood test for methylated DNA sensitive for colorectal cancer.Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemiaIllegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy.Prognostic impact of IKZF1 deletion in adults with common B-cell acute lymphoblastic leukemia.Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol.Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia.Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer.Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia.Molecular genetics of B-precursor acute lymphoblastic leukemiaFunction of Ikaros as a tumor suppressor in B cell acute lymphoblastic leukemiaRecurrent deletions of IKZF1 in pediatric acute myeloid leukemiaAdvances in the Biology of Acute Lymphoblastic Leukemia-From Genomics to the ClinicSynergism of FAK and tyrosine kinase inhibition in Ph+ B-ALL.IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia.Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: association with cytogenetics and clinical features.What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?Genomic characterization of childhood acute lymphoblastic leukemia.COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia.Targeting of heme oxygenase-1 attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positive B-ALL.Lineage-Specific Genes Are Prominent DNA Damage Hotspots during Leukemic Transformation of B Cell Precursors.Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells.Genomic profiling of high-risk acute lymphoblastic leukemia.
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P2860
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@en
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@nl
type
label
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@en
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@nl
prefLabel
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@en
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@nl
P2093
P50
P1433
P1476
Identification and molecular c ...... Ematologiche dell'Adulto Acute
@en
P2093
Antonella Vitale
Daniela Cilloni
Domenico Russo
Fabrizio Pane
Francesca Messa
Luciana Impera
Pier Paolo Piccaluga
Sabina Chiaretti
Sabrina Colarossi
Stefania Paolini
P304
P356
10.1182/BLOOD-2008-08-173963
P407
P50
P577
2009-07-09T00:00:00Z