The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein.
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Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasiaEpithelial stem cells: an epigenetic and Wnt-centric perspective.Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells.Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells.Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice.Pygo2 siRNA Inhibit the Growth and Increase Apoptosis of U251 Cell by Suppressing Histone H3K4 Trimethylation.Evidence of a novel role for Pygopus in rRNA transcription.Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway.The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression.Abnormal nuclear expression of Pygopus-2 in human primary hepatocellular carcinoma correlates with a poor prognosis.Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer
P2860
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P2860
The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
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name
The transcriptional activity o ...... rotein (CREB)-binding protein.
@en
The transcriptional activity o ...... sponse-element-binding protein
@nl
type
label
The transcriptional activity o ...... rotein (CREB)-binding protein.
@en
The transcriptional activity o ...... sponse-element-binding protein
@nl
prefLabel
The transcriptional activity o ...... rotein (CREB)-binding protein.
@en
The transcriptional activity o ...... sponse-element-binding protein
@nl
P2093
P2860
P356
P1433
P1476
The transcriptional activity o ...... rotein (CREB)-binding protein.
@en
P2093
Cathy Popadiuk
Kenneth R Kao
Phillip G P Andrews
Zhijian He
P2860
P304
P356
10.1042/BJ20090134
P407
P577
2009-08-27T00:00:00Z