about
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The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signalingbeta-Catenin is a Nek2 substrate involved in centrosome separation.Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complexEssential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functionsAn intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acidWnt signal transduction pathwaysWnt signaling: the good and the badThe many faces and functions of β-cateninAllosteric Remodelling of the Histone H3 Binding Pocket in the Pygo2 PHD Finger Triggered by Its Binding to the B9L/BCL9 Co-FactorEvolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2Pygopus residues required for its binding to Legless are critical for transcription and developmentPygo1 and Pygo2 roles in Wnt signaling in mammalian kidney developmentBCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regenerationPygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylationNotch signaling through tramtrack bypasses the mitosis promoting activity of the JNK pathway in the mitotic-to-endocycle transition of Drosophila follicle cells.Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells.The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin.Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations.Coop functions as a corepressor of Pangolin and antagonizes Wingless signalingWnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling.Canonical wingless signaling regulates cone cell specification in the Drosophila retinaStriking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progressionThe role of pygopus in the differentiation of intracardiac valves in Drosophila.Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.Wnt signaling in disease and in development.Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.Genetic interaction of Lobe with its modifiers in dorsoventral patterning and growth of the Drosophila eye.An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eyeIdentification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells.Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer.The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3betaPygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells.Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors.Downregulation of miR-432 activates Wnt/β-catenin signaling and promotes human hepatocellular carcinoma proliferation.Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries.The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with DishevelledAn analysis of the gene expression program of mammalian neural progenitor cellsAn ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.
P2860
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P2860
description
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Mai 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: May 2002)
@en
vedecký článok (publikovaný 2002-05)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd in 2002-05)
@nl
наукова стаття, опублікована в травні 2002
@uk
مقالة علمية (نشرت في مايو 2002)
@ar
name
A new nuclear component of the Wnt signalling pathway
@ast
A new nuclear component of the Wnt signalling pathway
@en
A new nuclear component of the Wnt signalling pathway
@nl
type
label
A new nuclear component of the Wnt signalling pathway
@ast
A new nuclear component of the Wnt signalling pathway
@en
A new nuclear component of the Wnt signalling pathway
@nl
prefLabel
A new nuclear component of the Wnt signalling pathway
@ast
A new nuclear component of the Wnt signalling pathway
@en
A new nuclear component of the Wnt signalling pathway
@nl
P2093
P3181
P356
P1433
P1476
A new nuclear component of the Wnt signalling pathway
@en
P2093
Fiona Townsley
Hannah Musisi
Mariann Bienz
Rina Rosin-Arbesfeld
P2888
P304
P3181
P356
10.1038/NCB786
P407
P577
2002-05-01T00:00:00Z
P6179
1011278151