Distinct profiles of REST interactions with its target genes at different stages of neuronal development. - Wikidata - wikimedia - TriplyDB

Distinct profiles of REST interactions with its target genes at different stages of neuronal development.

Distinct profiles of REST interactions with its target genes at different stages of neuronal development.

http://www.wikidata.org/entity/Q39847561

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Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases(1,2,3)Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival Binding of hnRNP H and U2AF65 to respective G-codes and a poly-uridine tract collaborate in the N50-5'ss selection of the REST N exon in H69 cells Stem cells have different needs for REST REST and CoREST modulate neuronal subtype specification, maturation and maintenance.A comparative genomics approach to identifying the plasticity transcriptome.Oct4 targets regulatory nodes to modulate stem cell function REST regulates distinct transcriptional networks in embryonic and neural stem cells.Rest-mediated regulation of extracellular matrix is crucial for neural development.Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation.Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting.Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells.p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiation Molecular pathways and targets in prostate cancer Neuronatin promotes neural lineage in ESCs via Ca(2+) signaling Silencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner.REST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.REST regulates DYRK1A transcription in a negative feedback loop.Coassembly of REST and its cofactors at sites of gene repression in embryonic stem cells.Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres.Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor.RE1 silencing transcription factor (REST) negatively regulates ALL1-fused from chromosome 1q (AF1q) gene transcription.Significant expansion of the REST/NRSF cistrome in human versus mouse embryonic stem cells: potential implications for neural development The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells.Directing neuronal differentiation of primary neural progenitor cells by gene knockdown approach.Effects on promoter activity of common SNPs in 5' region of GABRB3 exon 1A.Brain selective transgene expression in zebrafish using an NRSE derived motif.DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation REST regulation of neural development: From outside-in?RE1 silencing transcription factor is involved in regulating neuron-specific expression of alpha-internexin and neurofilament genes.REST and the RESTless: in stem cells and beyond Targeting histone deacetylases for the treatment of disease Sp1 and Sp3 regulate transcription of the cyclin-dependent kinase 5 regulatory subunit 2 (p39) promoter in neuronal cells.Suppression of Sin3A activity promotes differentiation of pluripotent cells into functional neurons.Involvement of REST corepressor 3 in prognosis of human hepatitis B.

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Distinct profiles of REST interactions with its target genes at different stages of neuronal development.

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Molecular Biology of the Cell

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Miyoko Street

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Nikolai D Belyaev

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Sandra Wilde

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Thomas Bee

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Yuh-Man Sun

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P2860

CoREST: a functional corepressor required for regulation of neural-specific gene expression

REST repression of neuronal genes requires components of the hSWI.SNF complex

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

Transcriptional regulatory networks in Saccharomyces cerevisiae

Regulation of neuronal traits by a novel transcriptional complex

Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment

A small modulatory dsRNA specifies the fate of adult neural stem cells

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