Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia.
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Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemiaThe miRacle in Pancreatic Cancer by miRNAs: Tiny Angels or Devils in Disease ProgressionClinical significance of microRNAs in chronic and acute human leukemiaMicroRNAs as diagnostic and prognostic biomarkers in colorectal cancerThe functional role of microRNA in acute lymphoblastic leukemia: relevance for diagnosis, differential diagnosis, prognosis, and therapymiRNA biogenesis: biological impact in the development of cancerDNA methylation and microRNA dysregulation in cancerEpigenetics: a new mechanism of regulation of heart failure?Epigenetics in acute kidney injuryA kinase-independent function of CDK6 links the cell cycle to tumor angiogenesisDrug targets for cell cycle dysregulators in leukemogenesis: in silico docking studiesEpigenetic inactivation of the miR-124-1 in haematological malignancies.miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro.Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/BFrequent and distinct aberrations of DNA methylation patterns in fibrolamellar carcinoma of the liver.Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.miRNAs in human cancer.Identification of miR‑124a as a novel diagnostic and prognostic biomarker in non‑small cell lung cancer for chemotherapy.Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemiaForced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatmentImplication of microRNAs in drug resistance for designing novel cancer therapyMethylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer.Recurrent amplification at 7q21.2 Targets CDK6 gene in primary myxofibrosarcomas and identifies CDK6 overexpression as an independent adverse prognosticator.Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research.Epigenetic alteration and microRNA dysregulation in cancerMicroRNA-124-3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1.MicroRNA Methylation in Colorectal Cancer.Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer.MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cellsMicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neckUp-regulation of miR-9 expression predicate advanced clinicopathological features and poor prognosis in patients with hepatocellular carcinomaTargeting cell cycle regulators in hematologic malignancies.Regulation and methylation of tumor suppressor miR-124 by androgen receptor in prostate cancer cells.Regulation of RAB5C is important for the growth inhibitory effects of MiR-509 in human precursor-B acute lymphoblastic leukemia.Epigenetic mechanisms of pulmonary hypertension.Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms.Converging miRNA functions in diverse brain disorders: a case for miR-124 and miR-126.Regulation of Nuclear Receptor Nur77 by miR-124.miR-124 regulates fetal pulmonary epithelial cell maturation.
P2860
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P2860
Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@en
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@nl
type
label
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@en
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@nl
prefLabel
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@en
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@nl
P2093
P50
P1433
P1476
Epigenetic silencing of the tu ...... acute lymphoblastic leukemia.
@en
P2093
Amaia Vilas-Zornoza
Anabel Heiniger
Antonio Jiménez-Velasco
Antonio Torres
Edurne San José-Eneriz
Eva Bandrés
Gloria Abizanda
José Rifón
José Román-Gomez
Leire Gárate
P304
P356
10.1158/0008-5472.CAN-08-4025
P407
P577
2009-05-12T00:00:00Z