Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells.

Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells.

Item
http://www.wikidata.org/entity/Q39855621
Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis.Targeting p53 by small molecules in hematological malignancies.Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).Epstein-Barr nuclear antigen 1 induces expression of the cellular microRNA hsa-miR-127 and impairing B-cell differentiation in EBV-infected memory B cells. New insights into the pathogenesis of Burkitt lymphomaIs MDM2 SNP309 Variation a Risk Factor for Head and Neck Carcinoma?: An Updated Meta-Analysis Based on 11,552 Individuals.Interference with p53 functions in human viral infections, a target for novel antiviral strategies?Virus-encoded microRNA contributes to the molecular profile of EBV-positive Burkitt lymphomasTreatment with a BH3 mimetic overcomes the resistance of latency III EBV (+) cells to p53-mediated apoptosis.Constitutive autophagy contributes to resistance to TP53-mediated apoptosis in Epstein-Barr virus-positive latency III B-cell lymphoproliferations.Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2.Human Oncoviruses and p53 Tumor Suppressor Pathway Deregulation at the Origin of Human Cancers.Role of the MDM2 SNP309 polymorphism in the initiation and early age of onset of nasopharyngeal carcinoma
P2860

Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells.

Item
http://www.wikidata.org/entity/Q39855621
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Activation of p53 by MDM2 anta ...... tive Burkitt's lymphoma cells.
@en
Activation of p53 by MDM2 anta ...... effects on Epstein-Barr virus
@nl
type
label
Activation of p53 by MDM2 anta ...... tive Burkitt's lymphoma cells.
@en
Activation of p53 by MDM2 anta ...... effects on Epstein-Barr virus
@nl
prefLabel
Activation of p53 by MDM2 anta ...... tive Burkitt's lymphoma cells.
@en
Activation of p53 by MDM2 anta ...... effects on Epstein-Barr virus
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P6179
P698
P921
P356
P1433
P1476
Activation of p53 by MDM2 anta ...... tive Burkitt's lymphoma cells.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P6179
P698
P921