EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants.
about
Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeresRECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombinationArtemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint responseDNA end resection: many nucleases make light workTelomere rapid deletion regulates telomere length in Arabidopsis thalianaNucleases in homologous recombination as targets for cancer therapyCdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere MaintenanceCompeting roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination.Control of the yeast telomeric senescence survival pathways of recombination by the Mec1 and Mec3 DNA damage sensors and RPA.Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance.Polymerase epsilon is required to maintain replicative senescence.The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome proteinInactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterilityExonuclease 1-dependent and independent mismatch repairDrosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore componentsTERRA promotes telomere shortening through exonuclease 1-mediated resection of chromosome endsCell cycle-dependent regulation of yeast telomerase by Ku.Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsDNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore.Linear chromosome maintenance in the absence of essential telomere-capping proteins.Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase.Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice.AdnAB: a new DSB-resecting motor-nuclease from mycobacteria.Nonadditivity in the recognition of single-stranded DNA by the schizosaccharomyces pombe protection of telomeres 1 DNA-binding domain, Pot1-DBDCDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptationDistinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNAFission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres.Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targetingRegulation of Ku-DNA association by Yku70 C-terminal tail and SUMO modificationThe DNA damage response pathway contributes to the stability of chromosome III derivatives lacking efficient replicators.Rif1 supports the function of the CST complex in yeast telomere capping.Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiaeChromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms.Ku must load directly onto the chromosome end in order to mediate its telomeric functions.The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeresA novel checkpoint and RPA inhibitory pathway regulated by Rif1Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining
P2860
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P2860
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@en
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@nl
type
label
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@en
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@nl
prefLabel
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@en
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@nl
P2860
P356
P1433
P1476
EXO1-dependent single-stranded ...... ding yeast yku70Delta mutants.
@en
P2093
David Lydall
Laura Maringele
P2860
P304
P356
10.1101/GAD.225102
P577
2002-08-01T00:00:00Z