TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. - Wikidata - wikimedia - TriplyDB

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

http://www.wikidata.org/entity/Q39867711

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WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ The hippo signaling pathway in development and cancer A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites Hippo pathway-independent restriction of TAZ and YAP by angiomotin Structural and functional analysis of the YAP-binding domain of human TEAD2 Regulation of TAZ in cancer Emerging role of Hippo pathway in gastric and other gastrointestinal cancers The TEAD Family and Its Oncogenic Role in Promoting Tumorigenesis A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas Emerging role of cell polarity proteins in breast cancer progression and metastasis The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment Structural insights into the YAP and TEAD complex Structural basis of YAP recognition by TEAD4 in the Hippo pathway Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Yes-associated protein 1 is activated and functions as an oncogene in meningiomas.Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation.Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex.Transcriptional co-activator with PDZ-binding motif overexpression promotes cell proliferation and transcriptional co-activator with PDZ-binding motif deficiency induces cell cycle arrest in neuroblastoma.Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches.The Hippo pathway in disease and therapy: cancer and beyond TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ PTPN14 forms a complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic function The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase.TAZ expression as a prognostic indicator in colorectal cancer.Hippo signaling: growth control and beyond.Overexpression of YAP and TAZ is an independent predictor of prognosis in colorectal cancer and related to the proliferation and metastasis of colon cancer cells.Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activation KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma.A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ.Transcriptional co-activator TAZ sustains proliferation and tumorigenicity of neuroblastoma by targeting CTGF and PDGF-β.AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma.Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions.Concise Review: Stem Cell Microenvironment on a Chip: Current Technologies for Tissue Engineering and Stem Cell Biology The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1.YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.TAZ suppresses NFAT5 activity through tyrosine phosphorylation.A basal-like breast cancer-specific role for SRF-IL6 in YAP-induced cancer stemness Structural and functional insights into the TEAD-YAP complex in the Hippo signaling pathway.CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity

P2860

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P2860

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

http://www.wikidata.org/entity/Q39867711

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@en

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@nl

type

label

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@en

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@nl

prefLabel

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@en

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@nl

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P1433

Journal of Biological Chemistry

P1476

TEADs mediate nuclear retention of TAZ to promote oncogenic transformation.

@en

P2093

Caixia Huang

http://www.w3.org/2001/XMLSchema#string

Chun Jye Lim

http://www.w3.org/2001/XMLSchema#string

Li Shen Loo

http://www.w3.org/2001/XMLSchema#string

Siew Wee Chan

http://www.w3.org/2001/XMLSchema#string

Wanjin Hong

http://www.w3.org/2001/XMLSchema#string

Yaan Fun Chong

http://www.w3.org/2001/XMLSchema#string

P2860

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

TEAD mediates YAP-dependent gene induction and growth control

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

Identification of Fat4 as a candidate tumor suppressor gene in breast cancers

P304

14347-14358

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scholarly article

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10.1074/JBC.M901568200

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21

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284

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2009-03-26T00:00:00Z

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19324876

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2682883

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