Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen.

Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen.

Item
http://www.wikidata.org/entity/Q39870530
Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisCellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.Restriction of human polyomavirus BK virus DNA replication in murine cells and extractsLoss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB.Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.E1A 12S and 13S of the transformation-defective adenovirus type 12 strain CS-1 inactivate proteins of the RB family, permitting transactivation of the E2F-dependent promoter.
P2860

Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen.

Item
http://www.wikidata.org/entity/Q39870530
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@en
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@nl
type
label
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@en
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@nl
prefLabel
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@en
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@nl
P1433
P1476
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P921
P932
P1433
P1476
Inactivation of the retinoblas ...... imian virus 40 large T antigen
@en
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P921
P932