Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen.
about
Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisCellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.Restriction of human polyomavirus BK virus DNA replication in murine cells and extractsLoss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.p130 is dispensable in peripheral T lymphocytes: evidence for functional compensation by p107 and pRB.Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.E1A 12S and 13S of the transformation-defective adenovirus type 12 strain CS-1 inactivate proteins of the RB family, permitting transactivation of the E2F-dependent promoter.
P2860
Q24540044-792F8092-4C41-4314-81DA-C512287FE954Q33772346-31C5418D-50A3-43D7-A52B-1C4C8444020BQ34662543-EC9E6050-671C-4C56-981D-8C812A1FE1FBQ34985587-A7AEEB20-D75F-445B-B959-332FCF75EECDQ35859848-44EF0248-3B6A-4999-80EC-08F41FD9FB5AQ36570729-8C065C1B-D085-43A1-81A2-4BB22CD54C6BQ36571152-F4D0BE1C-868D-425E-85C2-331D7BB4D65AQ37191960-A2FC723D-5A14-43AD-8990-17307D49B00BQ39455963-AFB6567D-BA78-4651-AD61-ABE7CD0F3C4EQ39631226-926C5227-7F10-4D9E-B9C5-43269ABDB29AQ39878446-78DAD2FF-B25E-4A0B-BE70-40F653AAFE80Q40015482-7632CE28-83DF-4ACA-B0E5-3CD87771237E
P2860
Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@en
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@nl
type
label
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@en
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@nl
prefLabel
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@en
Inactivation of the retinoblas ...... mian virus 40 large T antigen.
@nl
P2860
P1433
P1476
Inactivation of the retinoblas ...... imian virus 40 large T antigen
@en
P2093
Christensen JB
Imperiale MJ
P2860
P304
P407
P577
1995-06-01T00:00:00Z