Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.
about
Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperoneBurkitt's lymphoma: new insights into molecular pathogenesisStructural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigenCytoplasmic localization of human cdc25C during interphase requires an intact 14-3-3 binding siteIGF-IR-dependent expression of Survivin is required for T-antigen-mediated protection from apoptosis and proliferation of neural progenitors.The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.E1A blocks hyperphosphorylation of p130 and p107 without affecting the phosphorylation status of the retinoblastoma protein.The Epstein-Barr virus protein BRLF1 activates S phase entry through E2F1 induction.Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts.Removal of a small C-terminal region of JCV and SV40 large T antigens has differential effects on transformationT antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisSimian virus 40 large T antigen and two independent T-antigen segments sensitize cells to apoptosis following genotoxic damageInhibition of post-transcriptional RNA processing by CDK inhibitors and its implication in anti-viral therapy.The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2).Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoproteinA simian virus 40 large T-antigen segment containing amino acids 1 to 127 and expressed under the control of the rat elastase-1 promoter produces pancreatic acinar carcinomas in transgenic mice.Truncated N-terminal mutants of SV40 large T antigen as minimal immortalizing agents for CNS cellsExpression of the small T antigen of Lymphotropic Papovavirus is sufficient to transform primary mouse embryo fibroblasts.Induction of tumor antigen-specific immunity in vivo by a novel vaccinia vector encoding safety-modified simian virus 40 T antigen.Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.Regulation of the retinoblastoma proteins by the human herpesviruses.Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation.Polyomavirus large T antigen binds the transcriptional coactivator protein p300.Novel mechanisms of E2F induction by BK virus large-T antigen: requirement of both the pRb-binding and the J domains.Polyomavirus T antigens: molecular chaperones for multiprotein complexes.J domain-independent regulation of the Rb family by polyomavirus large T antigenpRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppressionHuman cytomegalovirus pp71 stimulates cell cycle progression by inducing the proteasome-dependent degradation of the retinoblastoma family of tumor suppressors.Dissecting the contribution of p16(INK4A) and the Rb family to the Ras transformed phenotype.Cellular transformation of mouse embryo fibroblasts in the absence of activator E2Fs.Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain.Activation of the tumor-specific death effector apoptin and its kinase by an N-terminal determinant of simian virus 40 large T antigen.The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function.Simian virus 40 large T antigen's association with the CUL7 SCF complex contributes to cellular transformation.
P2860
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P2860
Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@ast
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@en
type
label
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@ast
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@en
prefLabel
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@ast
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@en
P2093
P2860
P1433
P1476
Simian virus 40 large T antige ...... elated proteins p130 and p107.
@en
P2093
P2860
P304
P407
P577
1996-05-01T00:00:00Z