Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent.
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Binding of human immunodeficiency virus type 1 to CD4 and CXCR4 receptors differentially regulates expression of inflammatory genes and activates the MEK/ERK signaling pathway.CCR8 on human thymocytes functions as a human immunodeficiency virus type 1 coreceptor.Infection of cells expressing CXCR4 mutants lacking N-glycosylation at the N-terminal extracellular domain is enhanced for R5X4-dualtropic human immunodeficiency virus type-1.Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide ReceptorSodium lauryl sulfate abrogates human immunodeficiency virus infectivity by affecting viral attachmentPotent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor useEffects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.Fine definition of the CXCR4-binding region on the V3 loop of feline immunodeficiency virus surface glycoprotein.Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infectionEvidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usagePatterns of CCR5, CXCR4, and CCR3 usage by envelope glycoproteins from human immunodeficiency virus type 1 primary isolates.Differentiation of promonocytic U937 subclones into macrophagelike phenotypes regulates a cellular factor(s) which modulates fusion/entry of macrophagetropic human immunodeficiency virus type 1.Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitroDifferential tropism and replication kinetics of human immunodeficiency virus type 1 isolates in thymocytes: coreceptor expression allows viral entry, but productive infection of distinct subsets is determined at the postentry level.Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture.N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates.Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells.Antigenically distinct conformations of CXCR4.Differential tropism and chemokine receptor expression of human immunodeficiency virus type 1 in neonatal monocytes, monocyte-derived macrophages, and placental macrophagesCXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells.Inhibition of HIV-1 infection by human α-defensin-5, a natural antimicrobial peptide expressed in the genital and intestinal mucosae.Direct measurement of thermal stability of expressed CCR5 and stabilization by small molecule ligands.Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CTShared usage of the chemokine receptor CXCR4 by the feline and human immunodeficiency viruses.Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loopLangerhans cell tropism of human immunodeficiency virus type 1 subtype A through F isolates derived from different transmission groupsSusceptibility of HIV type 2 primary isolates to CCR5 and CXCR4 monoclonal antibodies, ligands, and small molecule inhibitorsCoreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations.Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor.Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell decline.Promonocytic U937 subclones expressing CD4 and CXCR4 are resistant to infection with and cell-to-cell fusion by T-cell-tropic human immunodeficiency virus type 1.Inhibition of HIV-1 entry by antibodies: potential viral and cellular targetsThe neutral glycosphingolipid globotriaosylceramide promotes fusion mediated by a CD4-dependent CXCR4-utilizing HIV type 1 envelope glycoprotein.Derivation and characterization of a simian immunodeficiency virus SIVmac239 variant with tropism for CXCR4.
P2860
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P2860
Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Inhibition of human immunodefi ...... pe and virus strain dependent.
@en
Inhibition of human immunodefi ...... lonal antibody to a coreceptor
@nl
type
label
Inhibition of human immunodefi ...... pe and virus strain dependent.
@en
Inhibition of human immunodefi ...... lonal antibody to a coreceptor
@nl
prefLabel
Inhibition of human immunodefi ...... pe and virus strain dependent.
@en
Inhibition of human immunodefi ...... lonal antibody to a coreceptor
@nl
P2093
P2860
P1433
P1476
Inhibition of human immunodefi ...... ype and virus strain dependent
@en
P2093
Clapham PR
McKnight A
Wilkinson D
P2860
P304
P407
P50
P577
1997-02-01T00:00:00Z