Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
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Oncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapyWild-type herpes simplex virus 1 blocks programmed cell death and release of cytochrome c but not the translocation of mitochondrial apoptosis-inducing factor to the nuclei of human embryonic lung fibroblasts.The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells.Herpes simplex virus 1 blocks caspase-3-independent and caspase-dependent pathways to cell death.Herpes simplex virus type 1 renders infected cells resistant to cytotoxic T-lymphocyte-induced apoptosis.Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins.Induction and prevention of apoptosis in human HEp-2 cells by herpes simplex virus type 1.Herpes simplex virus type 1 latency-associated transcript expression protects trigeminal ganglion neurons from apoptosis.The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein.Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo.Protein kinase B/Akt is present in activated form throughout the entire replicative cycle of deltaU(S)3 mutant virus but only at early times after infection with wild-type herpes simplex virus 1Estrogen enhances the efficacy of an oncolytic HSV-1 mutant in the treatment of estrogen receptor-positive breast cancer.The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BADNF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infectionHerpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosisPhylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent mannerIn transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.The herpes simplex virus 1 protein kinase US3 is required for protection from apoptosis induced by the virusHerpes simplex virus type 1 infection of activated cytotoxic T cells: Induction of fratricide as a mechanism of viral immune evasionClearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes.Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.Cellular players in the herpes simplex virus dependent apoptosis balancing act.Herpes simplex virus inhibits apoptosis through the action of two genes, Us5 and Us3.Herpes simplex virus type 1 blocks the apoptotic host cell defense mechanisms that target Bcl-2 and manipulates activation of p38 mitogen-activated protein kinase to improve viral replicationExposure of HEp-2 cells to stress conditions influences antinuclear antibody reactivity.Herpes simplex virus blocks apoptosis by precluding mitochondrial cytochrome c release independent of caspase activation in infected human epithelial cells.Antiviral and virucidal activities of nα-cocoyl-L-arginine ethyl ester.ICP0 gene expression is a herpes simplex virus type 1 apoptotic trigger
P2860
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P2860
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
@en
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
@nl
type
label
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
@en
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
@nl
prefLabel
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
@en
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells.
@nl
P2860
P1433
P1476
Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells
@en
P2093
P2860
P304
P407
P577
1997-03-01T00:00:00Z