ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway.
about
Identification of chemosensitivity nodes for vinblastine through small interfering RNA high-throughput screens.Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer.Melanoma: a model for testing new agents in combination therapies.Genetic variants of NOXA and MCL1 modify the risk of HPV16-associated squamous cell carcinoma of the head and neck.Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivoDistribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells.Novel therapeutic approaches for small cell lung cancer: the future has arrivedYM-155 potentiates the effect of ABT-737 in malignant human glioma cells via survivin and Mcl-1 downregulation in an EGFR-dependent context.Targeting proliferation and survival pathways in head and neck cancer for therapeutic benefitCordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells.Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy.Current treatment of cutaneous squamous cancer and molecular strategies for its sensitization to new target-based drugs.Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin.Antihelminthic benzimidazoles potentiate navitoclax (ABT-263) activity by inducing Noxa-dependent apoptosis in non-small cell lung cancer (NSCLC) cell lines.MLN2238 synergizes BH3 mimetic ABT-263 in castration-resistant prostate cancer cells by induction of NOXA.RRM2 regulates Bcl-2 in head and neck and lung cancers: a potential target for cancer therapy.Apoptotic effect of cisplatin and cordycepin on OC3 human oral cancer cells.Platinum compounds sensitize ovarian carcinoma cells to ABT-737 by modulation of the Mcl-1/Noxa axis.Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma.RASSF1A and the BH3-only mimetic ABT-737 promote apoptosis in pediatric medulloblastoma cell lines.Cytotoxicity, drug combinability, and biological correlates of ABT-737 against acute lymphoblastic leukemia cells with MLL rearrangement.Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells.Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine.Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC.
P2860
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P2860
ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
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2009年學術文章
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name
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@en
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@nl
type
label
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@en
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@nl
prefLabel
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@en
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@nl
P2093
P2860
P356
P1476
ABT-737 synergizes with chemot ...... s via a Noxa-mediated pathway.
@en
P2093
Changyou Li
Daniel E Johnson
Neil S Patel
Rongxiu Li
P2860
P304
P356
10.1124/MOL.108.052969
P577
2009-02-25T00:00:00Z