Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.

Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.

Item
http://www.wikidata.org/entity/Q39897555
Structure-Function Elucidation of a New  -Conotoxin, Lo1a, from Conus longurionisBlockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculationsA synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.Conotoxins targeting nicotinic acetylcholine receptors: an overviewIdentification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins.Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle-type nAChRs, and the allosteric binding site of muscarinic M2 receptors.Discovery of a potent and selective α3β4 nicotinic acetylcholine receptor antagonist from an α-conotoxin synthetic combinatorial library.Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptorNicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability.Synthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.Fluorinated amino acids: compatibility with native protein structures and effects on protein-protein interactions.Molecular Engineering of Conus Peptides as Therapeutic Leads.
P2860

Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives.

Item
http://www.wikidata.org/entity/Q39897555
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2009 nî lūn-bûn
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2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Rational design of alpha-conot ...... ration of proline derivatives.
@en
Rational design of alpha-conot ...... ration of proline derivatives.
@nl
type
label
Rational design of alpha-conot ...... ration of proline derivatives.
@en
Rational design of alpha-conot ...... ration of proline derivatives.
@nl
prefLabel
Rational design of alpha-conot ...... ration of proline derivatives.
@en
Rational design of alpha-conot ...... ration of proline derivatives.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Rational design of alpha-conot ...... ration of proline derivatives.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932