Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells
about
Exploring the cellular accumulation of metal complexes.Multifaceted interplay between lipophilicity, protein interaction and luminescence parameters of non-intercalative ruthenium(II) polypyridyl complexes controlling cellular imaging and cytotoxic properties.In vitro anticancer activity of cis-diammineplatinum(II) complexes with β-diketonate leaving group ligandsMetal-Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation.Anticancer metallodrug research analytically painting the "omics" picture--current developments and future trends.A Photoactivatable Platinum(IV) Anticancer Complex Conjugated to the RNA Ligand Guanidinoneomycin.Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexesMultifunctional αvβ6 Integrin-Specific Peptide-Pt(IV) Conjugates for Cancer Cell Targeting.Guanidine platinum(II) complexes: synthesis, in vitro antitumor activity, and DNA interactions.Influence of reducing agents on the cytotoxic activity of platinum(IV) complexes: induction of G2/M arrest, apoptosis and oxidative stress in A2780 and cisplatin resistant A2780cis cell lines.Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential.Integrin-targeted delivery into cancer cells of a Pt(IV) pro-drug through conjugation to RGD-containing peptides.Mechanism of cellular accumulation of an iridium(III) pentamethylcyclopentadienyl anticancer complex containing a C,N-chelating ligand.A dinuclear ruthenium(II) complex as a one- and two-photon luminescent probe for biological Cu(2+) detection.Cellular uptake mechanisms of an antitumor ruthenium compound: the endosomal/lysosomal system as a target for anticancer metal-based drugs.Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells.The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(II) asymmetric complexes.Unsymmetric mono- and dinuclear platinum(IV) complexes featuring an ethylene glycol moiety: synthesis, characterization, and biological activity.Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells.Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells.Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds.Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019.Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin.Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes.Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339.EPR as a probe of the intracellular speciation of ruthenium(III) anticancer compounds.Synthesis and in vivo anticancer evaluation of poly(organo)phosphazene-based metallodrug conjugates.Near-infrared emitting iridium(iii) complexes for mitochondrial imaging in living cells.Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic.Improving the biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled phosholipidic nano-mixed micellar systems.
P2860
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P2860
Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
@zh-hant
name
Development of an experimental ...... pounds in adherent tumor cells
@en
Development of an experimental ...... ounds in adherent tumor cells.
@nl
type
label
Development of an experimental ...... pounds in adherent tumor cells
@en
Development of an experimental ...... ounds in adherent tumor cells.
@nl
prefLabel
Development of an experimental ...... pounds in adherent tumor cells
@en
Development of an experimental ...... ounds in adherent tumor cells.
@nl
P2860
P50
P356
P1476
Development of an experimental ...... pounds in adherent tumor cells
@en
P2093
Alexander E Egger
Christina Rappel
P2860
P356
10.1039/B810481F
P577
2009-01-01T00:00:00Z