[Pt(O,O'-acac)(gamma-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway
about
Targeting mitochondrial cell death pathway to overcome drug resistance with a newly developed iron chelateAntitumor activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in mouse xenograft model of breast cancer.Apoptosis by [Pt(O,O'-acac)(γ-acac)(DMS)] requires PKC-δ mediated p53 activation in malignant pleural mesothelioma.Sublethal concentrations of the platinum(II) complex [Pt(O,O'-acac)(gamma-acac)(DMS)] alter the motility and induce anoikis in MCF-7 cells.[Pt(O,O'-acac)(γ-acac)(DMS)] alters SH-SY5Y cell migration and invasion by the inhibition of Na+/H+ exchanger isoform 1 occurring through a PKC-ε/ERK/mTOR Pathway.Different apoptotic effects of [Pt(O,O'-acac)(γ-acac)(DMS)] and cisplatin on normal and cancerous human epithelial breast cells in primary cultureIn vitro anticancer activity of cis-diammineplatinum(II) complexes with β-diketonate leaving group ligandsIn Vitro and In Vivo Antitumor Activity of [Pt(O,O'-acac)(γ-acac)(DMS)] in Malignant Pleural MesotheliomaA new platinum(II) compound anticancer drug candidate with selective cytotoxicity for breast cancer cells.Inhibition of ZL55 cell proliferation by ADP via PKC-dependent signalling pathway.[Pt(O,O'-acac)(γ-acac)(DMS)] versus cisplatin: apoptotic effects in B50 neuroblastoma cells.Novel Platinum(II) compounds modulate insulin-degrading enzyme activity and induce cell death in neuroblastoma cells.Novel platinum(II) compounds with O,S bidentate ligands: synthesis, characterization, antiproliferative properties and biomolecular interactions.The Plasma Membrane Calcium ATPases and Their Role as Major New Players in Human Disease.Redox active copper chelate overcomes multidrug resistance in T-lymphoblastic leukemia cell by triggering apoptosis.First report of a haemagglutinin-induced apoptotic pathway in breast cancer cells.Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cellsDeveloping central nervous system and vulnerability to platinum compounds.Antitumour and antiangiogenic activities of [Pt(O,O'-acac)(γ-acac)(DMS)] in a xenograft model of human renal cell carcinoma.Mutagenic Tests Confirm That New Acetylacetonate Pt(II) Complexes Induce Apoptosis in Cancer Cells Interacting with Nongenomic Biological Targets.Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effectsA newly synthesized nickel chelate can selectively target and overcome multidrug resistance in cancer through redox imbalance both in vivo and in vitro.Platinum drugs and neurotoxicity: effects on intracellular calcium homeostasis.Photoactive platinum(ii) β-diketonates as dual action anticancer agents.Neurotoxic Effects of Platinum Compounds: Studies in vivo on Intracellular Calcium Homeostasis in the Immature Central Nervous System.CCL20 promotes migration and invasiveness of human cancerous breast epithelial cells in primary culture.Response of Cisplatin Resistant Skov-3 Cells to [Pt(-Acac)(γ-Acac)(DMS)] Treatment Revealed by a Metabolomic ¹H-NMR Study
P2860
Q28474590-03D19549-10D5-49C1-A029-7D3EFFB1FF2CQ33695015-51CB98D9-2B7D-450C-86C1-5313E13E5FE4Q33898584-7F2B73ED-6F12-4AC4-A704-DB97D89DE799Q34124807-B6E57FEA-C7F6-44FA-90A5-7CCABD55575EQ34459460-9C153A7E-2D03-4440-836C-91D78CC62A81Q34619471-F2BA6E02-BA12-4EE7-9BB8-71A6498588FEQ36032615-E27AAABB-4F98-4DE9-B556-DD04AE5E59A8Q36180331-AE55C822-3F93-431C-A323-D02643AA5CFCQ37211981-74BB38C9-D7AC-43FB-98AB-ED23A55C51F9Q38695721-151C6CC6-DF88-489A-8613-D5072CC81A2DQ38805298-55A2BA69-6A35-46D3-9EE6-7EF7A4B0D32BQ38934781-0B7CFB74-D496-4A05-A42F-653DEEA75C08Q39069003-3FA058A8-8CE2-45D6-8007-9E4EE0F9B763Q39342378-EE0977C1-593E-45C0-AA6C-5A2CC499EA95Q39575525-184CF249-E8D3-464B-812A-A4229E08D377Q39811230-F8EB27B9-E4ED-4B69-A8BB-5DB58596198EQ39900189-210CB85F-957C-4A95-A533-E319DE278317Q40631758-82B85831-A041-49FB-8914-0D41ACD61443Q41881241-2936940B-9DD4-441F-9C74-DBD141E9F525Q41944528-CF528880-AB50-4115-A07C-83134E0A069BQ42575787-A8FC048A-6777-4880-A047-145EC03EA4FFQ42795867-5CDC74E1-E8C4-445E-BF21-FB1864013E4BQ44508174-671554FD-618C-4CA0-95BF-7D23F847F81CQ46506519-F21DEC04-C1C7-4B23-B75E-B57C1170B5F0Q47724377-4B9F2E1A-1250-4157-B7FA-27CEA5726AB6Q48271829-A8C609A9-2F38-46E5-9318-88298F891CF3Q58691893-A0933B33-00CF-4256-B484-86B89A057FF8
P2860
[Pt(O,O'-acac)(gamma-acac)(DMS)], a new Pt compound exerting fast cytotoxicity in MCF-7 breast cancer cells via the mitochondrial apoptotic pathway
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@ast
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@en
type
label
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@ast
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@en
prefLabel
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@ast
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@en
P2093
P2860
P50
P356
P1476
[Pt(O,O'-acac)(gamma-acac)(DMS ...... itochondrial apoptotic pathway
@en
P2093
A Ciccarese
A Muscella
S A De Pascali
S Marsigliante
P2860
P356
10.1038/SJ.BJP.0707576
P407
P577
2007-11-19T00:00:00Z