(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor
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Identification of the plant compound geraniin as a novel Hsp90 inhibitorGambogic acid, a natural product inhibitor of Hsp90(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma.Impact of butyrate on PKM2 and HSP90β expression in human colon tissues of different transformation stages: a comparison of gene and protein dataSelective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir.Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cellsThe spectral properties of (-)-epigallocatechin 3-O-gallate (EGCG) fluorescence in different solvents: dependence on solvent polarityThe heat shock protein 90 inhibitor, (-)-epigallocatechin gallate, has anticancer activity in a novel human prostate cancer progression model.High-throughput screen of natural product libraries for hsp90 inhibitors.EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes.The Chemical Biology of Molecular Chaperones--Implications for Modulation of ProteostasisIdentification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach.In vitro mechanism for downregulation of ER-α expression by epigallocatechin gallate in ER+/PR+ human breast cancer cellsA Scaffold Merging Approach to Hsp90 C-terminal Inhibition: Synthesis and Evaluation of a Chimeric Library.HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1.Signal transduction and molecular targets of selected flavonoids.Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.The anticancer flavonoid chrysin induces the unfolded protein response in hepatoma cells.The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth.Molecular cochaperones: tumor growth and cancer treatment.Camellia sinensis in asymptomatic hyperuricemia: A meta-analysis of tea or tea extract effects on uric acid levels.Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?Green Tea and Bone Marrow Transplantation: From Antioxidant Activity to Enzymatic and Multidrug-resistance Modulation.Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects.Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons.Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold.Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review.Alternative approaches to Hsp90 modulation for the treatment of cancer.(-)-Epigallocatechin-3-gallate inhibits the replication cycle of hepatitis C virus.(-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2.Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitorsSynthesis and structure-activity relationships of EGCG analogues, a recently identified Hsp90 inhibitorTowards natural mimetics of metformin and rapamycin.Epigallocatechin-3-gallate exerts protective effects against heat stress through modulating stress-responsive transcription factors in poultry.Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development.Cardiosulfa induces heart deformation in zebrafish through the AhR-mediated, CYP1A-independent pathway.The HSP90 Family: Structure, Regulation, Function, and Implications in Health and Disease
P2860
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P2860
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor
@en
type
label
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor
@en
prefLabel
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor
@en
P2093
P2860
P356
P1433
P1476
(-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor
@en
P2093
Ellen C Henry
Thomas A Gasiewicz
Zhengyu Yin
P2860
P304
P356
10.1021/BI801637Q
P407
P577
2009-01-01T00:00:00Z