Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors. - Wikidata - wikimedia - TriplyDB

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

http://www.wikidata.org/entity/Q37130692

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Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.Development of noviomimetics that modulate molecular chaperones and manifest neuroprotective effects.Synthesis and Biological Evaluation of Stilbene Analogues as Hsp90 C-Terminal Inhibitors.Proteomic interrogation of HSP90 and insights for medical research.Development of Phenyl Cyclohexylcarboxamides as a Novel Class of Hsp90 C-terminal Inhibitors.Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain.Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors.BRAF and MEK Inhibitors: Use and Resistance in BRAF-Mutated Cancers.Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6

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Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

http://www.wikidata.org/entity/Q37130692

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2016

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

@en

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

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type

label

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

@en

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

@nl

prefLabel

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

@en

Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

@nl

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Chemistry: A European Journal

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Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.

@en

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Brian S J Blagg

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Chitra Subramanian

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Hashim F Motiwala

http://www.w3.org/2001/XMLSchema#string

Jacqueline Sanchez

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Jeffrey Holzbeierlein

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Katherine M Byrd

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Mark S Cohen

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Weiya Liu

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P2860

Ganetespib: research and clinical development

The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

Elucidation of the Hsp90 C-terminal inhibitor binding site

Derrubone, an inhibitor of the Hsp90 protein folding machinery

Targeting the dynamic HSP90 complex in cancer

HSP90 and the chaperoning of cancer

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

Hsp90 inhibitors identified from a library of novobiocin analogues.

Novobiocin: redesigning a DNA gyrase inhibitor for selective inhibition of hsp90.

Identification and initial SAR of silybin: an Hsp90 inhibitor.

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6921-6931

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scholarly article

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10.1002/CHEM.201504955

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20

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2016-04-01T00:00:00Z

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27037933

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4962924

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