PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways.
about
The impact of high and low dose ionising radiation on the central nervous systemRole of nuclear receptors in breast cancer stem cellsα-Linolenic Acid, A Nutraceutical with Pleiotropic Properties That Targets Endogenous Neuroprotective Pathways to Protect against Organophosphate Nerve Agent-Induced NeuropathologyDeveloping interventions for cancer-related cognitive dysfunction in childhood cancer survivorsInflammation and resolution are associated with upregulation of fatty acid β-oxidation in Zymosan-induced peritonitisInhibition of IkappaB kinase-beta protects dopamine neurons against lipopolysaccharide-induced neurotoxicityCyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expressionBlockade of Kv1.3 channels ameliorates radiation-induced brain injury.PPARalpha: energy combustion, hypolipidemia, inflammation and cancerThe PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice.Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions.Radiation-induced c-Jun activation depends on MEK1-ERK1/2 signaling pathway in microglial cells.Impact of breathing 100% oxygen on radiation-induced cognitive impairmentThe synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α.Fenofibrate decreases radiation sensitivity via peroxisome proliferator-activated receptor α-mediated superoxide dismutase induction in HeLa cells.Ligand-activated peroxisome proliferator-activated receptor-δ and -γ inhibit lipopolysaccharide-primed release of high mobility group box 1 through upregulation of SIRT1Radiation-induced cognitive impairment--from bench to bedsidePeroxisome proliferator-activated receptor alpha expression changes in human pregnant myometriumBehavioral paradigms to evaluate PPAR modulation in animal models of brain injury.Identification of the microRNA networks contributing to macrophage differentiation and functionOleoylethanolamide exerts anti-inflammatory effects on LPS-induced THP-1 cells by enhancing PPARα signaling and inhibiting the NF-κB and ERK1/2/AP-1/STAT3 pathways.Role of PPARs in Radiation-Induced Brain Injury.Tetrahydroxystilbene glucoside attenuates neuroinflammation through the inhibition of microglia activation.PPAR-α as a key nutritional and environmental sensor for metabolic adaptation.Targeting the peroxisome proliferator-activated receptors (PPARs) in spinal cord injury.Neuroprotective Mechanisms of PPARδ: Modulation of Oxidative Stress and Inflammatory Processes.Radiation-induced brain injury: A reviewICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs--threshold doses for tissue reactions in a radiation protection context.Interleukins in glioblastoma pathophysiology: implications for therapy.Long-term effects of ionising radiation on the brain: cause for concern?Radiation-induced brain damage, impact of Michael Robbins' work and the need for predictive biomarkers.Pharmacological interventions to treat or prevent neurocognitive decline after brain radiation.Redox regulation of inflammation: old elements, a new story.Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy.Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A ReviewAbietic acid inhibits UVB-induced MMP-1 expression in human dermal fibroblast cells through PPARα/γ dual activation.PPARα activation attenuates amyloid-β-dependent neurodegeneration by modulating Endo G and AIF translocation.Kukoamine A Prevents Radiation-Induced Neuroinflammation and Preserves Hippocampal Neurogenesis in Rats by Inhibiting Activation of NF-κB and AP-1.PPARδ prevents radiation-induced proinflammatory responses in microglia via transrepression of NF-κB and inhibition of the PKCα/MEK1/2/ERK1/2/AP-1 pathwayPPARs and lipid ligands in inflammation and metabolism.
P2860
Q26740230-1ED01888-16D1-42B7-A000-6D19CC4E13DCQ26750359-2E522407-5CE3-4FB7-A2FE-C370A4B320AFQ26777019-65B3003B-58BC-48FA-A9A1-EDF623900881Q26825655-00CA8527-BB41-45B6-847B-04070050EF6BQ27314814-DBB4544C-E952-489D-8758-5B77AB386ECCQ28577454-F6B0DECE-BDE5-4C4E-9DAB-84849CC7540AQ28583248-9D9F7188-B90B-43D3-A911-4311CE1175F1Q30708168-1FBFFC0B-3F47-4720-846C-BF7236F55BDBQ33805104-26A41E90-097A-42F8-B459-E7B21317E102Q33919749-24CD47B3-F8F9-4A8C-A5E3-368EBE8099F5Q34127988-C39AA948-D250-423D-95F8-A68618FD3C9CQ34273675-FD0638F3-00B6-4152-92A7-85FC07369842Q35064583-6D9FA722-99A2-4B26-9D78-010A8E749B71Q36127141-DD4DA906-F21A-4748-855D-27DF576DDC44Q36195955-D549B6F4-19E0-497B-901B-76CF9ACAA92CQ36291125-3347A667-614B-41B0-BC10-46BEA6254ECFQ36344693-8BB2AFEC-DD06-4218-BDA8-4326E39E1FF8Q37019621-871D42F8-05AE-48E3-A28E-7995303F4E55Q37226637-2A3B57D3-0DF9-4A86-A570-6C859C29944EQ37301675-890E07B7-79C6-4798-9ECB-D377F5268FB2Q37323879-FAE17096-2387-4109-B719-B14135E5B030Q37356420-BFF30803-1723-4B11-8839-7B9190D58D8DQ37358873-94C7D667-3E51-4E3E-91CB-4DCF6793B448Q37616202-D60FF0DB-B3A0-47D7-B07F-1FB8BDA93C9DQ37899155-9D53E969-39FA-4B53-8C8D-88ACA14A960EQ37963878-B0653E10-83C4-486F-9CF9-5088448A9D11Q38029608-0BE99B11-5FCD-499B-AE01-99F97DF32F3FQ38038330-F86550AD-4DB0-4195-AEB2-196BB10E9EF5Q38051761-47FA05E5-73CD-49FF-BEE4-439968E9D83BQ38055706-BA5A2B79-8049-4308-962A-2ED98FFE59F2Q38213111-99DBCB64-DAC1-4DA2-A345-6EBDA0E2166FQ38233137-F0E75B13-E057-414B-BCC5-9F220F4C98B8Q38244572-5007F119-B98F-4BBC-A6C8-B511EF2CD96AQ38546383-6D20CDDF-7499-4842-9777-A60080C8C59CQ38648782-441CB9D3-FF39-4279-B442-A954A5BBC09DQ38929931-9F3D7643-9446-42C0-9AD1-796E73EAD1A7Q38973115-3A6EFA64-261E-4D65-92AE-CE74838C3A85Q39213305-99B6EA3D-185C-4F0A-9AEE-946AF19CFEE9Q39386442-D0A3A083-66F2-45E4-B70B-35BED509D759Q41763780-A88C995F-4316-4D8E-9516-D5F02C6C40D4
P2860
PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@en
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@nl
type
label
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@en
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@nl
prefLabel
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@en
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@nl
P2093
P2860
P921
P1476
PPARalpha ligands inhibit radi ...... g NF-kappaB and AP-1 pathways.
@en
P2093
Fang-Chi Hsu
Mike E Robbins
Mitra Kooshki
Sriram Ramanan
Weiling Zhao
P2860
P304
P356
10.1016/J.FREERADBIOMED.2008.09.002
P577
2008-09-17T00:00:00Z