Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.
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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesUsing the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growthNeutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor modelTumor-Associated Macrophages and Neutrophils in Tumor MicroenvironmentThe Yin and Yang of Toll-like receptors in cancerLoss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute PancreatitisGenetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progressionNovel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function.Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancerTargeted delivery of interferon-alpha via fusion to anti-CD20 results in potent antitumor activity against B-cell lymphoma.Bone marrow-derived vascular modulatory cells in pulmonary arterial hypertension.Chemotherapy and tumor microenvironment of pancreatic cancer.Use of adenoviral vectors to target chemotherapy to tumor vascular endothelial cells suppresses growth of breast cancer and melanomaHuman proangiogenic circulating hematopoietic stem and progenitor cells promote tumor growth in an orthotopic melanoma xenograft model.Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors.FcRgamma activation regulates inflammation-associated squamous carcinogenesis.Stromal-dependent tumor promotion by MIF family members.Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic riskSuppression of autophagy by FIP200 deletion inhibits mammary tumorigenesisA self-contained enzyme activating prodrug cytotherapy for preclinical melanoma.Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in miceCell-delivered magnetic nanoparticles caused hyperthermia-mediated increased survival in a murine pancreatic cancer model.Differential macrophage programming in the tumor microenvironment.Exploiting natural anti-tumor immunity for metastatic renal cell carcinoma.Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA.Directing cell therapy to anatomic target sites in vivo with magnetic resonance targetingPlasmacytoid dendritic cells in the tumor microenvironment: immune targets for glioma therapeutics.IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.A cell-delivered and cell-activated SN38-dextran prodrug increases survival in a murine disseminated pancreatic cancer modelDual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death.The significance of macrophage phenotype in cancer and biomaterials.The metastasis-promoting roles of tumor-associated immune cellsTumor microenvironment in the brainEnhanced performance of macrophage-encapsulated nanoparticle albumin-bound-paclitaxel in hypo-perfused cancer lesionsThe role of tumor-associated macrophages in tumor vascularization.Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation.Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors.Myeloid cells in the tumor microenvironment: modulation of tumor angiogenesis and tumor inflammation.Genetic therapy for the nervous system.
P2860
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P2860
Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@en
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@nl
type
label
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@en
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@nl
prefLabel
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@en
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@nl
P2093
P50
P1433
P1476
Tumor-targeted interferon-alph ...... s tumor growth and metastasis.
@en
P2093
Davide Moi
Erika Zonari
Ferdinando Pucci
Michele De Palma
Rossella Galli
P304
P356
10.1016/J.CCR.2008.09.004
P50
P577
2008-10-01T00:00:00Z