Engineering viable foot-and-mouth disease viruses with increased thermostability as a step in the development of improved vaccines.
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Viral quasispecies evolutionA Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid ParticlesSubunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence TimeRational Engineering of Recombinant Picornavirus Capsids to Produce Safe, Protective Vaccine AntigenStructure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine designTruncated Bovine Integrin Alpha-v/Beta-6 as a Universal Capture Ligand for FMD Diagnosis.Viral genome segmentation can result from a trade-off between genetic content and particle stability.Evaluation of a genetically modified foot-and-mouth disease virus vaccine candidate generated by reverse geneticsInterferon-γ induced by in vitro re-stimulation of CD4+ T-cells correlates with in vivo FMD vaccine induced protection of cattle against disease and persistent infectionAnalysis of SAT type foot-and-mouth disease virus capsid proteins and the identification of putative amino acid residues affecting virus stability.Exploring the Balance between DNA Pressure and Capsid Stability in Herpesviruses and Phages.Picosecond infrared laser-induced all-atom nonequilibrium molecular dynamics simulation of dissociation of viruses.Identification of Positively Charged Residues in Enterovirus 71 Capsid Protein VP1 Essential for Production of Infectious Particles.Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditionsVaccination against foot-and-mouth disease virus: strategies and effectiveness.Virus engineering: functionalization and stabilization.Three-dimensional structure of foot-and-mouth disease virus and its biological functions.An increase in acid resistance of foot-and-mouth disease virus capsid is mediated by a tyrosine replacement of the VP2 histidine previously associated with VP0 cleavage.Foot-and-mouth disease vaccines: progress and problems.SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased ThermostabilityThe pH Stability of Foot-and-Mouth Disease Virus Particles Is Modulated by Residues Located at the Pentameric Interface and in the N Terminus of VP1.Single amino acid substitution of VP1 N17D or VP2 H145Y confers acid-resistant phenotype of type Asia1 foot-and-mouth disease virus.Selection and characterization of an acid-resistant mutant of serotype O foot-and-mouth disease virus.Equine Rhinitis A Virus Mutants with Altered Acid Resistance Unveil a Key Role of VP3 and Intrasubunit Interactions in the Control of the pH Stability of the Aphthovirus Capsid.A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid resistance.A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid lability and confer resistance to acid-dependent uncoating inhibition.Requirements for improved vaccines against foot-and-mouth disease epidemics.Systematic study of the genetic response of a variable virus to the introduction of deleterious mutations in a functional capsid region.Assembly, Engineering and Applications of Virus-Based Protein Nanoparticles.Quantitatively probing propensity for structural transitions in engineered virus nanoparticles by single-molecule mechanical analysis.Eggshell-inspired biomineralization generates vaccines that do not require refrigeration.The use of databases, data mining and immunoinformatics in vaccinology: where are we?Alumina-encapsulated vaccine formulation with improved thermostability and immunogenicity.
P2860
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P2860
Engineering viable foot-and-mouth disease viruses with increased thermostability as a step in the development of improved vaccines.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@en
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@nl
type
label
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@en
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@nl
prefLabel
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@en
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@nl
P2093
P2860
P356
P1433
P1476
Engineering viable foot-and-mo ...... elopment of improved vaccines.
@en
P2093
Mauricio G Mateu
Roberto Mateo
Verónica Rincón
P2860
P304
12232-12240
P356
10.1128/JVI.01553-08
P407
P577
2008-10-01T00:00:00Z