Impaired regulation of tumor suppressor p53 caused by mutations in the xeroderma pigmentosum DDB2 gene: mutual regulatory interactions between p48(DDB2) and p53.
about
Tumor-prone phenotype of the DDB2-deficient miceRecognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease.Xeroderma pigmentosum complementation group E protein (XPE/DDB2): purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties.Damaged DNA binding protein 2 plays a role in breast cancer cell growthNRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer.Impaired repair of cyclobutane pyrimidine dimers in human keratinocytes deficient in p53 and p63RETRACTED: DDB2, an essential mediator of premature senescenceRegulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNAOverexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis.DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability.Functional regulation of the DNA damage-recognition factor DDB2 by ubiquitination and interaction with xeroderma pigmentosum group C protein.Association of nucleotide excision repair pathway gene polymorphisms with gastric cancer and atrophic gastritis risksMultiple skin cancers in adults with mutations in the XP-E (DDB2) DNA repair gene.Damaged DNA binding protein 2 in reactive oxygen species (ROS) regulation and premature senescenceDDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen.Tumor regression by phenethyl isothiocyanate involves DDB2.Nucleotide excision repair deficiency in melanoma in response to UVA.Phosphorylation and ubiquitination-dependent degradation of CABIN1 releases p53 for transactivation upon genotoxic stressA novel cis-acting element from the 3'UTR of DNA damage-binding protein 2 mRNA links transcriptional and post-transcriptional regulation of gene expressionDDB2 decides cell fate following DNA damage.Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression.Damaged-DNA Binding Protein-2 Drives Apoptosis Following DNA Damage.Ddb1 controls genome stability and meiosis in fission yeast.Human papilloma virus type16 E6 deregulates CHK1 and sensitizes human fibroblasts to environmental carcinogens independently of its effect on p53.
P2860
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P2860
Impaired regulation of tumor suppressor p53 caused by mutations in the xeroderma pigmentosum DDB2 gene: mutual regulatory interactions between p48(DDB2) and p53.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Impaired regulation of tumor s ...... atory interactions between p48
@nl
Impaired regulation of tumor s ...... ons between p48(DDB2) and p53.
@en
type
label
Impaired regulation of tumor s ...... atory interactions between p48
@nl
Impaired regulation of tumor s ...... ons between p48(DDB2) and p53.
@en
prefLabel
Impaired regulation of tumor s ...... atory interactions between p48
@nl
Impaired regulation of tumor s ...... ons between p48(DDB2) and p53.
@en
P2093
P2860
P1476
Impaired regulation of tumor s ...... ons between p48(DDB2) and p53.
@en
P2093
Cristin O'Shea
Stuart Linn
Toshiki Itoh
P2860
P304
P356
10.1128/MCB.23.21.7540-7553.2003
P407
P577
2003-11-01T00:00:00Z