Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells. - Wikidata - wikimedia - TriplyDB

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.

http://www.wikidata.org/entity/Q39948728

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Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function When stem cells grow old: phenotypes and mechanisms of stem cell aging Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications Autophagy in stem cells.Genetic regulation of thymocyte progenitor aging Hematopoietic stem cell niche maintenance during homeostasis and regeneration Age-dependent dysregulation of innate immunity Epigenetic regulation of hematopoietic stem cell aging Stem cell heterogeneity: implications for aging and regenerative medicine Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion Hematopoietic Stem Cells in Regenerative Medicine: Astray or on the Path?Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells, and the Bone Marrow Microenvironment Immunosenescence in renal transplantation: a changing balance of innate and adaptive immunity Impact of genomic damage and ageing on stem cell function Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors Accumulation of DNA damage in the aged hematopoietic stem cell compartment Single cell transcriptomics reveals unanticipated features of early hematopoietic precursors Cdc42 and aging of hematopoietic stem cells.Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.Loss of P2Y₁₄ results in an arresting response to hematological stress Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice Latexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth.Concise review: hematopoietic stem cell aging and the prospects for rejuvenation Clonal-level responses of functionally distinct hematopoietic stem cells to trophic factors.Enhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade.Measuring the aging process in stem cells Immune aging, dysmetabolism, and inflammation in neurological diseases.Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation.A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged.Index sorting resolves heterogeneous murine hematopoietic stem cell populations Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells.Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate.Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells.Hematopoietic lineage skewing and intestinal epithelia degeneration in aged mice with telomerase RNA component deletion.HSC Aging and Senescent Immune Remodeling.

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P2860

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.

http://www.wikidata.org/entity/Q39948728

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2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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type

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Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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Journal of Experimental Medicine

P1476

Clonal analysis reveals multip ...... rine hematopoietic stem cells.

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P2093

Brad Dykstra

http://www.w3.org/2001/XMLSchema#string

Gerald de Haan

http://www.w3.org/2001/XMLSchema#string

Jaring Schreuder

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Martha Ritsema

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Sandra Olthof

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P2860

Animal cell differentiation patterns suppress somatic evolution

In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation

Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Cell intrinsic alterations underlie hematopoietic stem cell aging.

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

Age-associated activation of epigenetically repressed genes in the mouse

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2691-2703

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10.1084/JEM.20111490

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22110168

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