Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing. - Wikidata - wikimedia - TriplyDB

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

http://www.wikidata.org/entity/Q39958205

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RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site Splicing regulation: from a parts list of regulatory elements to an integrated splicing code Functional MAPT haplotypes: bridging the gap between genotype and neuropathology The role of tau in neurodegenerative diseases and its potential as a therapeutic target Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging A novel mutation in CLCN1 associated with feline myotonia congenita Structural Basis for Stabilization of the Tau Pre-mRNA Splicing Regulatory Element by Novantrone (Mitoxantrone)Targeting mRNA for Alzheimer's and related dementias.Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease Ametantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.Identification of tau stem loop RNA stabilizers.Three repeat isoforms of tau inhibit assembly of four repeat tau filaments A birth of bipartite exon by intragenic deletion Targeting Abeta and tau in Alzheimer's disease, an early interim report Template-directed synthesis of a small molecule-antisense conjugate targeting an mRNA structure.Structural and functional analysis of the Rous Sarcoma virus negative regulator of splicing and demonstration of its activation by the 9G8 SR protein Bottom-up design of small molecules that stimulate exon 10 skipping in mutant MAPT pre-mRNA RNA Structures as Mediators of Neurological Diseases and as Drug Targets.The role of short RNA loops in recognition of a single-hairpin exon derived from a mammalian-wide interspersed repeat.Structural determinants for alternative splicing regulation of the MAPT pre-mRNA An intronic structure enabled by a long-distance interaction serves as a novel target for splicing correction in spinal muscular atrophy Tau mutations in neurodegenerative diseases.The Conservation and Function of RNA Secondary Structure in Plants.PSF suppresses tau exon 10 inclusion by interacting with a stem-loop structure downstream of exon 10.Rational therapeutic approaches to progressive supranuclear palsy.Pick one, but be quick: 5' splice sites and the problems of too many choices.Aberrant splicing in neurological diseases.Complexity of the alternative splicing landscape in plants.A day in the life of the spliceosome Exon-skipping antisense oligonucleotides to correct missplicing in neurogenetic diseases.Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing.Targeting a pre-mRNA structure with bipartite antisense molecules modulates tau alternative splicing.RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events.Mitoxantrone analogues as ligands for a stem-loop structure of tau pre-mRNA.Modulation of alternative splicing by long-range RNA structures in Drosophila.Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing.Alternative Splicing as a Target for Cancer Treatment.Exploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNA Identification of Ligands for the Tau Exon 10 Splicing Regulatory Element RNA by Using Dynamic Combinatorial Chemistry RNA Processing and Human Disorders

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Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

http://www.wikidata.org/entity/Q39958205

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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2006年學術文章

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name

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@en

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@nl

type

label

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@en

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@nl

prefLabel

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@en

Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@nl

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Journal of Biological Chemistry

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Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.

@en

P2093

Christina Muratore

http://www.w3.org/2001/XMLSchema#string

Christine P Donahue

http://www.w3.org/2001/XMLSchema#string

Jane Y Wu

http://www.w3.org/2001/XMLSchema#string

Kenneth S Kosik

http://www.w3.org/2001/XMLSchema#string

Michael S Wolfe

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P2860

Mfold web server for nucleic acid folding and hybridization prediction

Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta

Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17

Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Neurodegenerative tauopathies

Modulation of RNA function by oligonucleotides recognizing RNA structure.

Aberrant splicing of tau pre-mRNA caused by intronic mutations associated with the inherited dementia frontotemporal dementia with parkinsonism linked to chromosome 17.

Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2.

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10.1074/JBC.C600143200

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33

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