Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
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Development of Human Membrane Transporters: Drug Disposition and PharmacogeneticsPopulation pharmacokinetics of oral baclofen in pediatric patients with cerebral palsyPopulation pharmacokinetics of clozapine and its primary metabolite norclozapine in Chinese patients with schizophrenia.Tips and traps analyzing pediatric PK data.What is the right dose for children?Towards evidence-based dosing regimens in children on the basis of population pharmacokinetic pharmacodynamic modelling.The development of UDP-glucuronosyltransferases 1A1 and 1A6 in the pediatric liverInter-individual variation in morphine clearance in children.A bodyweight-dependent allometric exponent for scaling clearance across the human life-span.Population pharmacokinetics and maximum a posteriori probability Bayesian estimator of abacavir: application of individualized therapy in HIV-infected infants and toddlers.Pharmacokinetics of Morphine and Its Metabolites in Infants and Young Children After Congenital Heart SurgeryPharmacological treatment of neonatal pain: in search of a new equipoiseSimultaneous pharmacokinetic modeling of gentamicin, tobramycin and vancomycin clearance from neonates to adults: towards a semi-physiological function for maturation in glomerular filtrationPain in Intellectually Disabled Children: Towards Evidence-Based Pharmacotherapy?From pediatric covariate model to semiphysiological function for maturation: part I-extrapolation of a covariate model from morphine to Zidovudine.From Pediatric Covariate Model to Semiphysiological Function for Maturation: Part II-Sensitivity to Physiological and Physicochemical PropertiesAdaptive trials in paediatric development: dealing with heterogeneity and uncertainty in pharmacokinetic differences in children.The allometric exponent for scaling clearance varies with age: a study on seven propofol datasets ranging from preterm neonates to adults.The role of population PK-PD modelling in paediatric clinical research.Advances in paediatric pharmacokinetics.Profound changes in drug metabolism enzymes and possible effects on drug therapy in neonates and children.Pharmacogenetics and individualized therapy in children: immunosuppressants, antidepressants, anticancer and anti-inflammatory drugs.Neonatal pharmacology: extensive interindividual variability despite limited size.Pharmacokinetic and pharmacogenetic determinants and considerations in chemotherapy selection and dosing in infants.Biomarkers and clinical tools in critically ill children: are we heading toward tailored drug therapy?Prediction of morphine clearance in the paediatric population : how accurate are the available pharmacokinetic models?Population pharmacometrics in support of analgesics studies.Critical incidents related to opioid infusions in children: a five-year review and analysis.Drug metabolism for the paediatrician.Ethics of drug research in the pediatric intensive care unit.Pharmacokinetics in neonatal prescribing: evidence base, paradigms and the future.Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.Children in clinical trials: towards evidence-based pediatric pharmacotherapy using pharmacokinetic-pharmacodynamic modeling.Clinical pharmacology of analgosedatives in neonates: ways to improve their safe and effective use.Mechanistic Population Pharmacokinetics of Morphine in Neonates With Abstinence Syndrome After Oral Administration of Diluted Tincture of Opium.Paracetamol and morphine for infant and neonatal pain; still a long way to go?Morphine Pharmacodynamics in Mechanically Ventilated Preterm Neonates Undergoing Endotracheal Suctioning.Prediction of morphine dose in humans.Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics.Decreased Morphine Clearance in Neonates With Hypoxic Ischemic Encephalopathy Receiving Hypothermia.
P2860
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P2860
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@en
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@nl
type
label
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@en
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@nl
prefLabel
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@en
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@nl
P2093
P2860
P50
P1476
Morphine glucuronidation in preterm neonates, infants and children younger than 3 years.
@en
P2093
Catherijne A J Knibbe
Elke H J Krekels
Gijs W E Santen
Johannes N van den Anker
Meindert Danhof
Richard A van Lingen
Sinno H P Simons
P2860
P304
P356
10.2165/00003088-200948060-00003
P577
2009-01-01T00:00:00Z
P6179
1015423758