Transcriptional activation by the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen is facilitated by an N-terminal chromatin-binding motif.
about
Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocketKaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen modulates K1 expression through its cis-acting elements within the terminal repeats.Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomesKaposi's Sarcoma Herpesvirus Genome PersistenceLANA binds to multiple active viral and cellular promoters and associates with the H3K4methyltransferase hSET1 complexIntrabodies targeting the Kaposi sarcoma-associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells.Activation of the Kaposi's sarcoma-associated herpesvirus major latency locus by the lytic switch protein RTA (ORF50).Conservation of complex nuclear localization signals utilizing classical and non-classical nuclear import pathways in LANA homologs of KSHV and RFHVKaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistenceBrd2/RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1.Phosphorylation of the chromatin binding domain of KSHV LANAAcetylation of the latency-associated nuclear antigen regulates repression of Kaposi's sarcoma-associated herpesvirus lytic transcription.Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANAKaposi's sarcoma-associated herpesvirus LANA-1 interacts with the short variant of BRD4 and releases cells from a BRD4- and BRD2/RING3-induced G1 cell cycle arrest.The internal Kaposi's sarcoma-associated herpesvirus LANA regions exert a critical role on episome persistenceRibosomal protein S6 interacts with the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus.Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.Determination of Kaposi's sarcoma-associated herpesvirus C-terminal latency-associated nuclear antigen residues mediating chromosome association and DNA binding.Murine gammaherpesvirus 68 LANA acts on terminal repeat DNA to mediate episome persistence.Role of Kaposi's sarcoma-associated herpesvirus C-terminal LANA chromosome binding in episome persistence.Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistenceThe latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency.Prototype foamy virus gag nuclear localization: a novel pathway among retrovirusesKaposi's sarcoma-associated herpesvirus-encoded LANA contributes to viral latent replication by activating phosphorylation of survivin.Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen: Replicating and Shielding Viral DNA during Viral Persistence.Primary lymphocyte infection models for KSHV and its putative tumorigenesis mechanisms in B cell lymphomas.Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma--associated Herpesvirus Lymphomas.ORF73 LANA homologs of RRV and MneRV2 contain an extended RGG/RG-rich nuclear and nucleolar localization signal that interacts directly with importin β1 for non-classical nuclear import.Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigenThe latency-associated nuclear antigen interacts with MeCP2 and nucleosomes through separate domainsDisruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus.Full-Length Isoforms of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Accumulate in the Cytoplasm of Cells Undergoing the Lytic Cycle of Replication.Target genes of the largest human SWI/SNF complex subunit control cell growth.Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces a strong bend on binding to terminal repeat DNA.Recruitment of the tumour suppressor protein p73 by Kaposi's Sarcoma Herpesvirus latent nuclear antigen contributes to the survival of primary effusion lymphoma cells.
P2860
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P2860
Transcriptional activation by the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen is facilitated by an N-terminal chromatin-binding motif.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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name
Transcriptional activation by ...... minal chromatin-binding motif.
@en
Transcriptional activation by ...... minal chromatin-binding motif.
@nl
type
label
Transcriptional activation by ...... minal chromatin-binding motif.
@en
Transcriptional activation by ...... minal chromatin-binding motif.
@nl
prefLabel
Transcriptional activation by ...... minal chromatin-binding motif.
@en
Transcriptional activation by ...... minal chromatin-binding motif.
@nl
P2860
P1433
P1476
Transcriptional activation by ...... rminal chromatin-binding motif
@en
P2093
Gerald A Matchett
Lai-Yee Wong
P2860
P304
10074-10085
P356
10.1128/JVI.78.18.10074-10085.2004
P407
P577
2004-09-01T00:00:00Z