Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells
about
Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cellsNanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity.Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancerCorrelation between Mcl-1 and pAKT protein expression in colorectal cancer.Beyond cell death - antiapoptotic Bcl-2 proteins regulate migration and invasion of colorectal cancer cells in vitroEpidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancerBcl-xL promotes metastasis independent of its anti-apoptotic activity.TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin.Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells.Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1.Inhibition of NANOG/NANOGP8 downregulates MCL-1 in colorectal cancer cells and enhances the therapeutic efficacy of BH3 mimeticsTargeting FLIP and Mcl-1 using a combination of aspirin and sorafenib sensitizes colon cancer cells to TRAIL.Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1.YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cellsCytomegalovirus and tumors: two players for one goal-immune escape.Race and subset analyses in clinical trials: time to get serious about data integration.Cetuximab-mediated cellular cytotoxicity is inhibited by HLA-E membrane expression in colon cancer cells.The expression of Mcl-1 in human cervical cancer and its clinical significance.Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with irinotecan: results of an open-label, phase 1 study.
P2860
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P2860
Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Bcl-x
@nl
Bcl-x(L) and Myeloid cell leuk ...... nce of colorectal cancer cells
@en
type
label
Bcl-x
@nl
Bcl-x(L) and Myeloid cell leuk ...... nce of colorectal cancer cells
@en
prefLabel
Bcl-x
@nl
Bcl-x(L) and Myeloid cell leuk ...... nce of colorectal cancer cells
@en
P2093
P2860
P921
P356
P1476
Bcl-x(L) and Myeloid cell leuk ...... nce of colorectal cancer cells
@en
P2093
Achim Weber
Arno Schad
Christoph-C Schimanski
Henning Schulze-Bergkamen
Lothar Hickmann
Markus Moehler
Martin-R Berger
Peter-R Galle
Roland Ehrenberg
Steffen Heeger
P2860
P304
P356
10.3748/WJG.14.3829
P407
P50
P577
2008-06-01T00:00:00Z