CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery. - Wikidata - wikimedia - TriplyDB

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

http://www.wikidata.org/entity/Q39974031

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YY1-binding sites provide central switch functions in the PARP-1 gene expression network Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration CTCF: master weaver of the genome Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis CTCF: an architectural protein bridging genome topology and function Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation Poly (ADP-ribose) in the pathogenesis of Parkinson's disease CTCF: the protein, the binding partners, the binding sites and their chromatin loops Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents - A Potential Therapy for Cancer Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity.Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.Changes in poly(ADP-ribosyl)ation patterns in workers exposed to BTX Targeting poly(ADP-ribose) polymerase activity for cancer therapy.Poly(ADP-ribosyl)ation acts in the DNA demethylation of mouse primordial germ cells also with DNA damage-independent roles.CHD1L Regulated PARP1-Driven Pluripotency and Chromatin Remodeling During the Early-Stage Cell Reprogramming Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription.Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism.Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activity Chromatin insulators: a role in nuclear organization and gene expression.Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation.Poly(ADP-Ribosyl)ation Affects Histone Acetylation and Transcription.Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding.Regulation of chromatin structure by poly(ADP-ribosyl)ation.The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein Modifications: Beyond the Usual Suspects' Review Series.Poly-ADP-ribose polymerase: machinery for nuclear processes.Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.PARP1 Differentially Interacts with Promoter region of DUX4 Gene in FSHD Myoblasts Vertebrate Protein CTCF and its Multiple Roles in a Large-Scale Regulation of Genome Activity PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis.Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.Multiple sclerosis etiology: beyond genes and environment.The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets.PARP-1 and PARP-2: New players in tumour development.Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation Role of PARP-1 in prostate cancer.Metabolic Signaling to Chromatin.Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer: Current Developments, Therapeutic Strategies, and Future Opportunities.

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P2860

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

http://www.wikidata.org/entity/Q39974031

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

@en

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

@nl

type

label

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

@en

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

@nl

prefLabel

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

@en

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

@nl

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Journal of Biological Chemistry

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CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery

@en

P2093

Barbara Cecchinelli

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Gabriella Zupi

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Giuseppe Riggio

http://www.w3.org/2001/XMLSchema#string

Lilia Calabrese

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Olga Sthandier

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Paola Caiafa

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P2860

The role of poly(ADP-ribose) in the DNA damage signaling network

Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

The fundamental role of epigenetic events in cancer

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers

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10.1074/JBC.M801170200

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32

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283

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Michele Zampieri

Tiziana Guastafierro

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2008-06-05T00:00:00Z

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18539602

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DNA methylation

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2494936

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