ATM protein kinase mediates full activation of Akt and regulates glucose transporter 4 translocation by insulin in muscle cells.
about
Pathogenesis of ataxia-telangiectasia: the next generation of ATM functionsImproved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasionRole of ataxia telangiectasia mutated in insulin signalling of muscle-derived cell lines and mouse soleus.Dysregulating IRES-dependent translation contributes to overexpression of oncogenic Aurora A Kinase.A role for AMPK in increased insulin action after serum starvationATM signalling and cancer.Ataxia telangiectasia mutated influences cytochrome c oxidase activity.ATM and GLUT1-S490 phosphorylation regulate GLUT1 mediated transport in skeletal muscle.Ataxia telangiectasia mutated kinase plays a protective role in β-adrenergic receptor-stimulated cardiac myocyte apoptosis and myocardial remodeling.Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.Tug of war between survival and death: exploring ATM function in cancer.Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity.Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways.Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.Chloroquine increases phosphorylation of AMPK and Akt in myotubes.Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance.ATM protein is located on presynaptic vesicles and its deficit leads to failures in synaptic plasticityThe Aspergillus nidulans ATM kinase regulates mitochondrial function, glucose uptake and the carbon starvation response.Impaired insulin-stimulated glucose transport in ATM-deficient mouse skeletal muscle.The ATM protein kinase and cellular redox signaling: beyond the DNA damage response.ATM protein kinase signaling, type 2 diabetes and cardiovascular disease.Dexamethasone improves redox state in ataxia telangiectasia cells by promoting an NRF2-mediated antioxidant response.Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways.ATM kinase sustains HER2 tumorigenicity in breast cancer.Dexamethasone partially rescues ataxia telangiectasia-mutated (ATM) deficiency in ataxia telangiectasia by promoting a shortened protein variant retaining kinase activity.Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells.Neurodegeneration in ataxia-telangiectasia: Multiple roles of ATM kinase in cellular homeostasis.Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.Individual Cytokines Modulate the Neurological Symptoms of ATM Deficiency in a Region Specific Manner(1,2,3)Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study.Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats.Does oxidative DNA damage cause atherosclerosis and metabolic syndrome?: new insights into which came first: the chicken or the egg.Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.Nutrient Limitation Inactivates Mrc1-to-Cds1 Checkpoint Signalling in Schizosaccharomyces pombe.Ataxia-Telangiectasia Mutated Kinase Deficiency Impairs Autophagic Response Early During Myocardial Infarction.Forward subtractive libraries containing genes transactivated by dexamethasone in ataxia-telangiectasia lymphoblastoid cells.
P2860
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P2860
ATM protein kinase mediates full activation of Akt and regulates glucose transporter 4 translocation by insulin in muscle cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@en
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@nl
type
label
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@en
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@nl
prefLabel
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@en
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@nl
P2093
P921
P1433
P1476
ATM protein kinase mediates fu ...... on by insulin in muscle cells.
@en
P2093
Da-Qing Yang
Jinghua He
Jody C Hibma
Marie-Jo Halaby
P304
P356
10.1016/J.CELLSIG.2008.04.011
P577
2008-04-26T00:00:00Z