How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha.
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The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic usePlasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo.Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular traffickingCytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking.Liver gene transfer of interkeukin-15 constructs that become part of circulating high density lipoproteins for immunotherapyCharacterization and favorable in vivo properties of heterodimeric soluble IL-15·IL-15Rα cytokine compared to IL-15 monomer.TNF stimulates nuclear export and secretion of IL-15 by acting on CRM1 and ARF6Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1Expression of interleukin-15 and interleukin-15Rα in monocytes of HIV type 1-infected patients with different courses of disease progression.Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum.Eosinophil crystalloid granules: structure, function, and beyond.Skeletal muscle interleukin 15 promotes CD8(+) T-cell function and autoimmune myositis.High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent mannerThe p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.Dendritic cell derived cytokines in human natural killer cell differentiation and activation.Functional extracellular eosinophil granules: novel implications in eosinophil immunobiology.Trans-presentation: a novel mechanism regulating IL-15 delivery and responses.Stimulating natural killer cells to protect against cancer: recent developments.Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion.Skeletal muscle IL-15/IL-15Rα and myofibrillar protein synthesis after resistance exercise.Molecular Consequences of Proprotein Convertase 1/3 (PC1/3) Inhibition in Macrophages for Application to Cancer Immunotherapy: A Proteomic Study.Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity.Forced homo- and heterodimerization of all gp130-type receptor complexes leads to constitutive ligand-independent signaling and cytokine-independent growth.New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity.Transcriptional regulation of IL-15 expression during hematopoiesis.Transcriptional regulation of mouse mast cell protease-2 by interleukin-15.IL-15 modulates the balance between Bcl-2 and Bim via a Jak3/1-PI3K-Akt-ERK pathway to promote CD8αα+ intestinal intraepithelial lymphocyte survival.Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm.Serum IL-15 and IL-15Rα levels are decreased in lean and obese physically active humans.Genetic variants in IL15 promoter affect transcription activity and intramuscular fat deposition in longissimus dorsi muscle of pigs.New IL-15 receptor-α splicing variants identified in intestinal epithelial Caco-2 cells.CD4 effector T cell differentiation is controlled by IL-15 that is expressed and presented in trans.
P2860
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P2860
How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
How a cytokine is chaperoned t ...... (IL-15)/IL-15 receptor alpha.
@en
How a cytokine is chaperoned t ...... r: lessons from interleukin-15
@nl
type
label
How a cytokine is chaperoned t ...... (IL-15)/IL-15 receptor alpha.
@en
How a cytokine is chaperoned t ...... r: lessons from interleukin-15
@nl
prefLabel
How a cytokine is chaperoned t ...... (IL-15)/IL-15 receptor alpha.
@en
How a cytokine is chaperoned t ...... r: lessons from interleukin-15
@nl
P2093
P2860
P356
P1476
How a cytokine is chaperoned t ...... (IL-15)/IL-15 receptor alpha.
@en
P2093
Elena Bulanova
Erwin H Duitman
Silvia Bulfone-Paus
Zane Orinska
P2860
P304
P356
10.1128/MCB.02178-07
P407
P50
P577
2008-05-27T00:00:00Z