In vivo drug metabolite identification in preclinical ADME studies by means of UPLC/TWIMS/high resolution-QTOF MS(E) and control comparison: cost and benefit of vehicle-dosed control samples.

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In vivo drug metabolite identification in preclinical ADME studies by means of UPLC/TWIMS/high resolution-QTOF MS(E) and control comparison: cost and benefit of vehicle-dosed control samples.

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年学术文章

@wuu

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh

2016年學術文章

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name

In vivo drug metabolite identi ...... /TWIMS/high resolution-QTOF MS

@nl

In vivo drug metabolite identi ...... vehicle-dosed control samples.

@en

type

Item

label

In vivo drug metabolite identi ...... /TWIMS/high resolution-QTOF MS

@nl

In vivo drug metabolite identi ...... vehicle-dosed control samples.

@en

prefLabel

In vivo drug metabolite identi ...... /TWIMS/high resolution-QTOF MS

@nl

In vivo drug metabolite identi ...... vehicle-dosed control samples.

@en

P1476

In vivo drug metabolite identi ...... vehicle-dosed control samples.

@en

P2093

Lukas Fiebig

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Ralf Laux

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Rudolf Binder

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Thomas Ebner

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P2860

Performance evaluation of a hybrid linear ion trap/orbitrap mass spectrometer

Electrospray ionization for mass spectrometry of large biomolecules

Data acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS.

Electrostatic axially harmonic orbital trapping: a high-performance technique of mass analysis

Orthogonal acceleration time-of-flight mass spectrometry.

Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis.

Metabolite identification by data-dependent accurate mass spectrometric analysis at resolving power of 60,000 in external calibration mode using an LTQ/Orbitrap.

An integrated method for metabolite detection and identification using a linear ion trap/Orbitrap mass spectrometer and multiple data processing techniques: application to indinavir metabolite detection.

An accurate-mass-based spectral-averaging isotope-pattern-filtering algorithm for extraction of drug metabolites possessing a distinct isotope pattern from LC-MS data.

Electrospray: from ions in solution to ions in the gas phase, what we know now.

P304

922-930

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P31

scholarly article

P356

10.3109/00498254.2016.1143138

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P407

English

P433

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P478

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P577

2016-02-19T00:00:00Z

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P698

26891802

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